FOG17589
EOG8573S0

sce:IST1

Genes: 28

SGD Description
Protein with positive role in the multivesicular body sorting pathway; functions and forms a complex with Did2p; recruitment to endosomes is mediated by the Vps2p-Vps24p subcomplex of ESCRT-III; also interacts with Vps4p


PomBase Description
MVB sorting pathway protein (predicted)


AspGD Description
Ortholog(s) have role in late endosome to vacuole transport via multivesicular body sorting pathway and Golgi apparatus, cytosol, endosome, nucleus localization


References

Dimaano C, et al. (2008 Feb). Ist1 regulates Vps4 localization and assembly.

Rue SM, et al. (2008 Feb). Novel Ist1-Did2 complex functions at a late step in multivesicular body sorting.

Beltrao P, et al. (2009 Jun 16). Evolution of phosphoregulation: comparison of phosphorylation patterns across yeast species.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Dudin O, et al. (2017 Apr). A systematic screen for morphological abnormalities during fission yeast sexual reproduction identifies a mechanism of actin aster formation for cell fusion.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%