FOG17588
EOG8573S3

sce:DID4

Genes: 34

SGD Description
Class E Vps protein of the ESCRT-III complex; required for sorting of integral membrane proteins into lumenal vesicles of multivesicular bodies, and for delivery of newly synthesized vacuolar enzymes to the vacuole, involved in endocytosis


PomBase Description
ESCRT III complex subunit Did4


AspGD Description
Ortholog(s) have role in asexual sporulation resulting in formation of a cellular spore, intralumenal vesicle formation and protein retention in Golgi apparatus, more


References

Davis CA, et al. (2000 Apr 15). Test of intron predictions reveals novel splice sites, alternatively spliced mRNAs and new introns in meiotically regulated genes of yeast.

Howard TL, et al. (2001 Jul). CHMP1 functions as a member of a newly defined family of vesicle trafficking proteins.

Babst M, et al. (2002 Aug). Escrt-III: an endosome-associated heterooligomeric protein complex required for mvb sorting.

Iwaki T, et al. (2007 Aug). Essential roles of class E Vps proteins for sorting into multivesicular bodies in Schizosaccharomyces pombe.

Xiao J, et al. (2007 Nov 30). Structural characterization of the ATPase reaction cycle of endosomal AAA protein Vps4.

Obita T, et al. (2007 Oct 11). Structural basis for selective recognition of ESCRT-III by the AAA ATPase Vps4.

Azmi IF, et al. (2008 Jan). ESCRT-III family members stimulate Vps4 ATPase activity directly or via Vta1.

Teis D, et al. (2008 Oct). Ordered assembly of the ESCRT-III complex on endosomes is required to sequester cargo during MVB formation.

Calvo IA, et al. (2009 Aug 12). Genome-wide screen of genes required for caffeine tolerance in fission yeast.

Stewart EV, et al. (2011 Apr 22). Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex.

Van Damme P, et al. (2012 Jul 31). N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

Pan X, et al. (2012 Nov 23). Identification of novel genes involved in DNA damage response by screening a genome-wide Schizosaccharomyces pombe deletion library.

Chen Z, et al. (2012 Oct). A genetic screen to discover pathways affecting cohesin function in Schizosaccharomyces pombe identifies chromatin effectors.

Bhutta MS, et al. (2014). A complex network of interactions between mitotic kinases, phosphatases and ESCRT proteins regulates septation and membrane trafficking in S. pombe.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Graml V, et al. (2014 Oct 27). A genomic Multiprocess survey of machineries that control and link cell shape, microtubule organization, and cell-cycle progression.

Mojardín L, et al. (2015). Chromosome segregation and organization are targets of 5'-Fluorouracil in eukaryotic cells.

Zhang X, et al. (2015 Oct 9). Characterization of Tamoxifen as an Antifungal Agent Using the Yeast Schizosaccharomyces Pombe Model Organism.

Burr R, et al. (2016 Jun 3). Mga2 Transcription Factor Regulates an Oxygen-responsive Lipid Homeostasis Pathway in Fission Yeast.

Dudin O, et al. (2017 Apr). A systematic screen for morphological abnormalities during fission yeast sexual reproduction identifies a mechanism of actin aster formation for cell fusion.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%