FOG17586
EOG8573S8

sce:SEC62

Genes: 33

SGD Description
Essential subunit of Sec63 complex; with Sec61 complex, Kar2p/BiP and Lhs1p forms a channel competent for SRP-dependent and post-translational SRP-independent protein targeting and import into the ER; cotranslationally N-acetylated by NatA; other members are Sec63p, Sec66p, and Sec72p


PomBase Description
ER protein translocation subcomplex subunit Sec62 (predicted)


AspGD Description
Putative SEC63 complex subunit; expression enhanced by maltose


References

Deshaies RJ, et al. (1989 Dec). SEC62 encodes a putative membrane protein required for protein translocation into the yeast endoplasmic reticulum.

Deshaies RJ, et al. (1991 Feb 28). Assembly of yeast Sec proteins involved in translocation into the endoplasmic reticulum into a membrane-bound multisubunit complex.

Panzner S, et al. (1995 May 19). Posttranslational protein transport in yeast reconstituted with a purified complex of Sec proteins and Kar2p.

Swennen D, et al. (1997 Feb). Cloning the Yarrowia lipolytica homologue of the Saccharomyces cerevisiae SEC62 gene.

Willer M, et al. (2003 Jan 30). Identification of novel protein-protein interactions at the cytosolic surface of the Sec63 complex in the yeast ER membrane.

Plath K, et al. (2004 Jan). Interactions between Sec complex and prepro-alpha-factor during posttranslational protein transport into the endoplasmic reticulum.

Sims AH, et al. (2005 May). Transcriptome analysis of recombinant protein secretion by Aspergillus nidulans and the unfolded-protein response in vivo.

Kim H, et al. (2006 Jul 25). A global topology map of the Saccharomyces cerevisiae membrane proteome.

Beltrao P, et al. (2009 Jun 16). Evolution of phosphoregulation: comparison of phosphorylation patterns across yeast species.

Van Damme P, et al. (2012 Jul 31). N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

Coradetti ST, et al. (2013 Aug). Analysis of a conserved cellulase transcriptional regulator reveals inducer-independent production of cellulolytic enzymes in Neurospora crassa.

Das J, et al. (2013 May 21). Cross-species protein interactome mapping reveals species-specific wiring of stress response pathways.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Beckley JR, et al. (2015 Dec). A Degenerate Cohort of Yeast Membrane Trafficking DUBs Mediates Cell Polarity and Survival.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 33 genes with posterior transmembrane prediction > 50%