FOG14446
EOG8FFBM0

sce:VPS20

Genes: 33

SGD Description
Myristoylated subunit of the ESCRT-III complex; the endosomal sorting complex required for transport of transmembrane proteins into the multivesicular body pathway to the lysosomal/vacuolar lumen; cytoplasmic protein recruited to endosomal membranes


PomBase Description
ESCRT III complex subunit Vps20


AspGD Description
Ortholog(s) have role in cellular response to lithium ion, cellular response to pH and filamentous growth of a population of unicellular organisms in response to neutral pH, more


References

Ashrafi K, et al. (1998 Oct 2). A role for Saccharomyces cerevisiae fatty acid activation protein 4 in regulating protein N-myristoylation during entry into stationary phase.

Howard TL, et al. (2001 Jul). CHMP1 functions as a member of a newly defined family of vesicle trafficking proteins.

Kranz A, et al. (2001 Mar). A family of small coiled-coil-forming proteins functioning at the late endosome in yeast.

Babst M, et al. (2002 Aug). Escrt-III: an endosome-associated heterooligomeric protein complex required for mvb sorting.

Yeo SC, et al. (2003 Oct 1). Vps20p and Vta1p interact with Vps4p and function in multivesicular body sorting and endosomal transport in Saccharomyces cerevisiae.

Xu W, et al. (2004 Dec). Multivesicular body-ESCRT components function in pH response regulation in Saccharomyces cerevisiae and Candida albicans.

Teo H, et al. (2004 Oct). ESCRT-II, an endosome-associated complex required for protein sorting: crystal structure and interactions with ESCRT-III and membranes.

Iwaki T, et al. (2007 Aug). Essential roles of class E Vps proteins for sorting into multivesicular bodies in Schizosaccharomyces pombe.

Onishi M, et al. (2007 Dec). Schizosaccharomyces pombe Sst4p, a conserved Vps27/Hrs homolog, functions downstream of phosphatidylinositol 3-kinase Pik3p to mediate proper spore formation.

Xiao J, et al. (2007 Nov 30). Structural characterization of the ATPase reaction cycle of endosomal AAA protein Vps4.

Beltrao P, et al. (2009 Jun 16). Evolution of phosphoregulation: comparison of phosphorylation patterns across yeast species.

Stewart EV, et al. (2011 Apr 22). Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex.

Calcagno-Pizarelli AM, et al. (2011 Dec 1). Rescue of Aspergillus nidulans severely debilitating null mutations in ESCRT-0, I, II and III genes by inactivation of a salt-tolerance pathway allows examination of ESCRT gene roles in pH signalling.

Nakase M, et al. (2012 Mar). Intracellular trafficking and ubiquitination of the Schizosaccharomyces pombe amino acid permease Aat1p.

Pan X, et al. (2012 Nov 23). Identification of novel genes involved in DNA damage response by screening a genome-wide Schizosaccharomyces pombe deletion library.

Das J, et al. (2013 May 21). Cross-species protein interactome mapping reveals species-specific wiring of stress response pathways.

Bhutta MS, et al. (2014). A complex network of interactions between mitotic kinases, phosphatases and ESCRT proteins regulates septation and membrane trafficking in S. pombe.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Peñalva MA, et al. (2014 Dec). Liaison alcaline: Pals entice non-endosomal ESCRTs to the plasma membrane for pH signaling.

Dudin O, et al. (2017 Apr). A systematic screen for morphological abnormalities during fission yeast sexual reproduction identifies a mechanism of actin aster formation for cell fusion.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%