FOG14439
EOG8FFBNN

sce:GET1

Genes: 5

SGD Description
Subunit of the GET complex; involved in insertion of proteins into the ER membrane; required for the retrieval of HDEL proteins from the Golgi to the ER in an ERD2 dependent fashion and for normal mitochondrial morphology and inheritance


References

Ho Y, et al. (2002 Jan 10). Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry.

Dimmer KS, et al. (2002 Mar). Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae.

Ando A, et al. (2005 Jul). Cooperative function of the CHD5-like protein Mdm39p with a P-type ATPase Spf1p in the maintenance of ER homeostasis in Saccharomyces cerevisiae.

Schuldiner M, et al. (2005 Nov 4). Exploration of the function and organization of the yeast early secretory pathway through an epistatic miniarray profile.

Auld KL, et al. (2006 Sep). The conserved ATPase Get3/Arr4 modulates the activity of membrane-associated proteins in Saccharomyces cerevisiae.

Schuldiner M, et al. (2008 Aug 22). The GET complex mediates insertion of tail-anchored proteins into the ER membrane.

Stefer S, et al. (2011 Aug 5). Structural basis for tail-anchored membrane protein biogenesis by the Get3-receptor complex.

Wang F, et al. (2011 Sep 2). The mechanism of tail-anchored protein insertion into the ER membrane.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 3 genes with posterior transmembrane prediction > 50%