FOG12676
EOG8KWHCJ

sce:MAG1

Genes: 32

SGD Description
3-methyl-adenine DNA glycosylase; involved in protecting DNA against alkylating agents; initiates base excision repair by removing damaged bases to create abasic sites that are subsequently repaired; protein abundance increases in response to DNA replication stress


PomBase Description
DNA-3-methyladenine glycosidase Mag2|DNA-3-methyladenine glycosylase Mag1


AspGD Description
Ortholog(s) have DNA-3-methyladenine glycosylase activity, damaged DNA binding activity, role in DNA dealkylation involved in DNA repair, base-excision repair, AP site formation and cytoplasm, nucleus localization


References

Berdal KG, et al. (1990 Dec). Cloning and expression in Escherichia coli of a gene for an alkylbase DNA glycosylase from Saccharomyces cerevisiae; a homologue to the bacterial alkA gene.

Chen J, et al. (1990 Dec). Saccharomyces cerevisiae 3-methyladenine DNA glycosylase has homology to the AlkA glycosylase of E. coli and is induced in response to DNA alkylation damage.

Bjørås M, et al. (1995 Apr 11). Purification and properties of the alkylation repair DNA glycosylase encoded the MAG gene from Saccharomyces cerevisiae.

Grandier-Vazeille X, et al. (2001 Aug 21). Yeast mitochondrial dehydrogenases are associated in a supramolecular complex.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 3 genes with posterior transmembrane prediction > 50%