FOG12675
EOG8KWHCQ

sce:TAF9

Genes: 29

SGD Description
Subunit (17 kDa) of TFIID and SAGA complexes; involved in RNA polymerase II transcription initiation and in chromatin modification, similar to histone H3


PomBase Description
SAGA complex/ transcription initiation factor Taf9


AspGD Description
Ortholog(s) have chromatin binding, protein complex scaffold activity and role in RNA polymerase II transcriptional preinitiation complex assembly, histone acetylation


References

Grant PA, et al. (1998 Jul 10). A subset of TAF(II)s are integral components of the SAGA complex required for nucleosome acetylation and transcriptional stimulation.

Birck C, et al. (1998 Jul 24). Human TAF(II)28 and TAF(II)18 interact through a histone fold encoded by atypical evolutionary conserved motifs also found in the SPT3 family.

Grant PA, et al. (1999 Feb 26). Expanded lysine acetylation specificity of Gcn5 in native complexes.

Sanders SL, et al. (2000 May 5). Identification of two novel TAF subunits of the yeast Saccharomyces cerevisiae TFIID complex.

Gangloff YG, et al. (2001 Apr). The histone fold is a key structural motif of transcription factor TFIID.

Selleck W, et al. (2001 Aug). A histone fold TAF octamer within the yeast TFIID transcriptional coactivator.

Gangloff YG, et al. (2001 Mar). Histone folds mediate selective heterodimerization of yeast TAF(II)25 with TFIID components yTAF(II)47 and yTAF(II)65 and with SAGA component ySPT7.

Sanders SL, et al. (2002 Aug). Molecular characterization of Saccharomyces cerevisiae TFIID.

Martinez E, et al. (2002 Dec). Multi-protein complexes in eukaryotic gene transcription.

Pray-Grant MG, et al. (2002 Dec). The novel SLIK histone acetyltransferase complex functions in the yeast retrograde response pathway.

Sanders SL, et al. (2002 Jul). Proteomics of the eukaryotic transcription machinery: identification of proteins associated with components of yeast TFIID by multidimensional mass spectrometry.

Leurent C, et al. (2002 Jul 1). Mapping histone fold TAFs within yeast TFIID.

Krogan NJ, et al. (2003 Dec). A Snf2 family ATPase complex required for recruitment of the histone H2A variant Htz1.

Le Masson I, et al. (2003 Sep). Yaf9, a novel NuA4 histone acetyltransferase subunit, is required for the cellular response to spindle stress in yeast.

Bittner CB, et al. (2004 Aug). Direct physical and functional interaction of the NuA4 complex components Yaf9p and Swc4p.

Mizuguchi G, et al. (2004 Jan 16). ATP-driven exchange of histone H2AZ variant catalyzed by SWR1 chromatin remodeling complex.

Wu PY, et al. (2004 Jul 23). Molecular architecture of the S. cerevisiae SAGA complex.

Kobor MS, et al. (2004 May). A protein complex containing the conserved Swi2/Snf2-related ATPase Swr1p deposits histone variant H2A.Z into euchromatin.

Zhang H, et al. (2004 Nov). The Yaf9 component of the SWR1 and NuA4 complexes is required for proper gene expression, histone H4 acetylation, and Htz1 replacement near telomeres.

Krogan NJ, et al. (2004 Sep 14). Regulation of chromosome stability by the histone H2A variant Htz1, the Swr1 chromatin remodeling complex, and the histone acetyltransferase NuA4.

Pray-Grant MG, et al. (2005 Jan 27). Chd1 chromodomain links histone H3 methylation with SAGA- and SLIK-dependent acetylation.

Georgakopoulos P, et al. (2013). The Spt-Ada-Gcn5 Acetyltransferase (SAGA) complex in Aspergillus nidulans.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%