FOG12678
EOG8KWHC6

sce:BET3

Genes: 35

SGD Description
Core component of transport protein particle (TRAPP) complexes I-III; TRAPP complexes are related multimeric guanine nucleotide-exchange factors for the GTPase Ypt1, regulating ER-Golgi traffic (TRAPPI), intra-Golgi traffic (TRAPPII), endosome-Golgi traffic (TRAPPII and III) and autophagy (TRAPPIII); hydrophilic homodimeric protein that acts in conjunction with SNARE proteins in targeting and fusion of ER to Golgi transport vesicles


PomBase Description
TRAPP complex subunit Bet3 (predicted)


AspGD Description
Ortholog(s) have Rab guanyl-nucleotide exchange factor activity and role in ER to Golgi vesicle-mediated transport, intra-Golgi vesicle-mediated transport


References

Rossi G, et al. (1995 Dec). BET3 encodes a novel hydrophilic protein that acts in conjunction with yeast SNAREs.

Sacher M, et al. (1998 May 1). TRAPP, a highly conserved novel complex on the cis-Golgi that mediates vesicle docking and fusion.

Sacher M, et al. (2001 Feb). TRAPP I implicated in the specificity of tethering in ER-to-Golgi transport.

Turnbull AP, et al. (2005 Mar 9). Structure of palmitoylated BET3: insights into TRAPP complex assembly and membrane localization.

Lynch-Day MA, et al. (2010 Apr 27). Trs85 directs a Ypt1 GEF, TRAPPIII, to the phagophore to promote autophagy.

Yip CK, et al. (2010 Nov). Molecular architecture of the TRAPPII complex and implications for vesicle tethering.

Wendland J, et al. (2011 Dec). Genome evolution in the eremothecium clade of the Saccharomyces complex revealed by comparative genomics.

Van Damme P, et al. (2012 Jul 31). N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

Pinar M, et al. (2015 Apr 7). TRAPPII regulates exocytic Golgi exit by mediating nucleotide exchange on the Ypt31 ortholog RabERAB11.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%