FOG04661
EOG8PG4J0

sce:CKA1

Genes: 32

SGD Description
Alpha catalytic subunit of casein kinase 2 (CK2); a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerases; regulates Fkh1p-mediated donor preference during mating-type switching


PomBase Description
serine/threonine protein kinase Cka1


AspGD Description
Ortholog(s) have protein kinase activity


References

Padmanabha R, et al. (1987 Feb 5). Casein kinase II of yeast contains two distinct alpha polypeptides and an unusually large beta subunit.

Chen-Wu JL, et al. (1988 Nov). Isolation, sequencing, and disruption of the CKA1 gene encoding the alpha subunit of yeast casein kinase II.

Amatruda JF, et al. (1992 Jun). Purification, characterization, and immunofluorescence localization of Saccharomyces cerevisiae capping protein.

Roussou I, et al. (1994 Jan). The Schizosaccharomyces pombe casein kinase II alpha and beta subunits: evolutionary conservation and positive role of the beta subunit.

Snell V, et al. (1994 May 1). Genetic analysis of cell morphogenesis in fission yeast--a role for casein kinase II in the establishment of polarized growth.

Krogan NJ, et al. (2002 Oct). RNA polymerase II elongation factors of Saccharomyces cerevisiae: a targeted proteomics approach.

Shimada M, et al. (2005 Sep 23). Regulation of Cdc2p and Cdc13p is required for cell cycle arrest induced by defective RNA splicing in fission yeast.

Hayashi T, et al. (2007 Dec). Rapamycin sensitivity of the Schizosaccharomyces pombe tor2 mutant and organization of two highly phosphorylated TOR complexes by specific and common subunits.

Das M, et al. (2009 Aug 11). The conserved NDR kinase Orb6 controls polarized cell growth by spatial regulation of the small GTPase Cdc42.

Roux AE, et al. (2010 Jun). A screen for genes involved in respiration control and longevity in Schizosaccharomyces pombe.

Snaith HA, et al. (2011 Jul 1). Characterization of Mug33 reveals complementary roles for actin cable-dependent transport and exocyst regulators in fission yeast exocytosis.

Tang Z, et al. (2012 Oct 1). Interacting factors and cellular localization of SR protein-specific kinase Dsk1.

De Souza CP, et al. (2013). Functional analysis of the Aspergillus nidulans kinome.

Cipak L, et al. (2013 Mar 15). Crosstalk between casein kinase II and Ste20-related kinase Nak1.

Wang J, et al. (2013 Sep 1). Epe1 recruits BET family bromodomain protein Bdf2 to establish heterochromatin boundaries.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Moreira-Ramos S, et al. (2015 Feb). Casein kinase 2 inhibits HomolD-directed transcription by Rrn7 in Schizosaccharomyces pombe.

Lee J, et al. (2017 Feb 20). Chromatin remodeller Fun30^Fft3 induces nucleosome disassembly to facilitate RNA polymerase II elongation.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 2 genes with posterior transmembrane prediction > 50%

FOG04662
EOG8PG4J0

sce:CKA2

Genes: 24

SGD Description
Alpha' catalytic subunit of casein kinase 2 (CK2); CK2 is a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerases; protein abundance increases in response to DNA replication stress; regulates Fkh1p-mediated donor preference during mating-type switching


References

Padmanabha R, et al. (1987 Feb 5). Casein kinase II of yeast contains two distinct alpha polypeptides and an unusually large beta subunit.

Padmanabha R, et al. (1990 Aug). Isolation, sequencing, and disruption of the yeast CKA2 gene: casein kinase II is essential for viability in Saccharomyces cerevisiae.

Krogan NJ, et al. (2002 Oct). RNA polymerase II elongation factors of Saccharomyces cerevisiae: a targeted proteomics approach.

Calvert ME, et al. (2008 Feb). Phosphorylation by casein kinase 2 regulates Nap1 localization and function.

Van Damme P, et al. (2012 Jul 31). N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%

FOG04663
EOG8PG4J0

sce:absent

Genes: 2

 





 

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%