FOG04664
EOG8PG4HP
sce:RFC4
Genes: 33
EOG8PG4HP
sce:RFC4
Genes: 33
SGD Description
Subunit of heteropentameric Replication factor C (RF-C); which is a DNA binding protein and ATPase that acts as a clamp loader of the proliferating cell nuclear antigen (PCNA) processivity factor for DNA polymerases delta and epsilon; relocalizes to the cytosol in response to hypoxia
PomBase Description
DNA replication factor C complex subunit Rfc4 (predicted)
AspGD Description
Ortholog(s) have role in DNA strand elongation involved in DNA replication, UV-damage excision repair and Elg1 RFC-like complex, cytosol, nucleus localization
References
Li X, et al. (1994 Aug 26). Cloning and characterization of the essential Saccharomyces cerevisiae RFC4 gene encoding the 37-kDa subunit of replication factor C.
Cullmann G, et al. (1995 Sep). Characterization of the five replication factor C genes of Saccharomyces cerevisiae.
Chen X, et al. (2000 Jun 9). Fidelity of eucaryotic DNA polymerase delta holoenzyme from Schizosaccharomyces pombe.
Alleva JL, et al. (2000 Mar 14). In vitro reconstitution of the Schizosaccharomyces pombe alternative excision repair pathway.
Mayer ML, et al. (2001 May). Identification of RFC(Ctf18p, Ctf8p, Dcc1p): an alternative RFC complex required for sister chromatid cohesion in S. cerevisiae.
Naiki T, et al. (2001 Sep). Chl12 (Ctf18) forms a novel replication factor C-related complex and functions redundantly with Rad24 in the DNA replication checkpoint pathway.
Kenna MA, et al. (2003 Apr). Mechanical link between cohesion establishment and DNA replication: Ctf7p/Eco1p, a cohesion establishment factor, associates with three different replication factor C complexes.
Bellaoui M, et al. (2003 Aug 15). Elg1 forms an alternative RFC complex important for DNA replication and genome integrity.
Majka J, et al. (2003 Mar 4). Yeast Rad17/Mec3/Ddc1: a sliding clamp for the DNA damage checkpoint.
Bowman GD, et al. (2004 Jun 17). Structural analysis of a eukaryotic sliding DNA clamp-clamp loader complex.
Kim J, et al. (2005). Contrasting effects of Elg1-RFC and Ctf18-RFC inactivation in the absence of fully functional RFC in fission yeast.
Bylund GO, et al. (2005 Jul). Replication protein A-directed unloading of PCNA by the Ctf18 cohesion establishment complex.
Ansbach AB, et al. (2008 Feb). RFCCtf18 and the Swi1-Swi3 complex function in separate and redundant pathways required for the stabilization of replication forks to facilitate sister chromatid cohesion in Schizosaccharomyces pombe.
Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).
| Mitochondrial localization predictions | ||
|---|---|---|
| Predotar | TargetP | MitoProt |
 |
 |
 |
| Raw data
|
||
| Phobius transmembrane predictions
0 genes with posterior transmembrane prediction > 50% |
||
FOG04665
EOG8PG4HP
sce:RFC3
Genes: 33
EOG8PG4HP
sce:RFC3
Genes: 33
SGD Description
Subunit of heteropentameric Replication factor C (RF-C); which is a DNA binding protein and ATPase that acts as a clamp loader of the proliferating cell nuclear antigen (PCNA) processivity factor for DNA polymerases delta and epsilon; relocalizes to the cytosol in response to hypoxia
PomBase Description
DNA replication factor C complex subunit Rfc3
AspGD Description
Ortholog(s) have ATPase activity, DNA clamp loader activity and role in UV-damage excision repair, leading strand elongation, mitotic DNA damage checkpoint, sister chromatid cohesion
References
Li X, et al. (1994 Feb 1). Molecular cloning and expression of the Saccharomyces cerevisiae RFC3 gene, an essential component of replication factor C.
Cullmann G, et al. (1995 Sep). Characterization of the five replication factor C genes of Saccharomyces cerevisiae.
Green CM, et al. (2000 Jan 13). A novel Rad24 checkpoint protein complex closely related to replication factor C.
Mayer ML, et al. (2001 May). Identification of RFC(Ctf18p, Ctf8p, Dcc1p): an alternative RFC complex required for sister chromatid cohesion in S. cerevisiae.
Naiki T, et al. (2001 Sep). Chl12 (Ctf18) forms a novel replication factor C-related complex and functions redundantly with Rad24 in the DNA replication checkpoint pathway.
Kenna MA, et al. (2003 Apr). Mechanical link between cohesion establishment and DNA replication: Ctf7p/Eco1p, a cohesion establishment factor, associates with three different replication factor C complexes.
Yao N, et al. (2003 Dec 12). Replication factor C clamp loader subunit arrangement within the circular pentamer and its attachment points to proliferating cell nuclear antigen.
Majka J, et al. (2003 Mar 4). Yeast Rad17/Mec3/Ddc1: a sliding clamp for the DNA damage checkpoint.
Goldman GH, et al. (2004 Apr). Aspergillus nidulans as a model system to characterize the DNA damage response in eukaryotes.
Bowman GD, et al. (2004 Jun 17). Structural analysis of a eukaryotic sliding DNA clamp-clamp loader complex.
Bylund GO, et al. (2005 Jul). Replication protein A-directed unloading of PCNA by the Ctf18 cohesion establishment complex.
Van Damme P, et al. (2012 Jul 31). N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
| Mitochondrial localization predictions | ||
|---|---|---|
| Predotar | TargetP | MitoProt |
 |
 |
 |
| Raw data
|
||
| Phobius transmembrane predictions
0 genes with posterior transmembrane prediction > 50% |
||
FOG04666
EOG8PG4HP
sce:RFC2
Genes: 33
EOG8PG4HP
sce:RFC2
Genes: 33
SGD Description
Subunit of heteropentameric Replication factor C (RF-C); RF-C is a DNA binding protein and ATPase that acts as a clamp loader of the proliferating cell nuclear antigen (PCNA) processivity factor for DNA polymerases delta and epsilon
PomBase Description
DNA replication factor C complex subunit Rfc2
AspGD Description
Ortholog(s) have DNA clamp loader activity and role in UV-damage excision repair, leading strand elongation, mitotic DNA replication checkpoint, sister chromatid cohesion
References
Noskov V, et al. (1994 May 11). The RFC2 gene encoding a subunit of replication factor C of Saccharomyces cerevisiae.
Cullmann G, et al. (1995 Sep). Characterization of the five replication factor C genes of Saccharomyces cerevisiae.
Reynolds N, et al. (1999 Jan 15). A key role for replication factor C in DNA replication checkpoint function in fission yeast.
Green CM, et al. (2000 Jan 13). A novel Rad24 checkpoint protein complex closely related to replication factor C.
Chen X, et al. (2000 Jun 9). Fidelity of eucaryotic DNA polymerase delta holoenzyme from Schizosaccharomyces pombe.
Alleva JL, et al. (2000 Mar 14). In vitro reconstitution of the Schizosaccharomyces pombe alternative excision repair pathway.
Kai M, et al. (2001 May). Fission yeast Rad17 associates with chromatin in response to aberrant genomic structures.
Mayer ML, et al. (2001 May). Identification of RFC(Ctf18p, Ctf8p, Dcc1p): an alternative RFC complex required for sister chromatid cohesion in S. cerevisiae.
Naiki T, et al. (2001 Sep). Chl12 (Ctf18) forms a novel replication factor C-related complex and functions redundantly with Rad24 in the DNA replication checkpoint pathway.
Kenna MA, et al. (2003 Apr). Mechanical link between cohesion establishment and DNA replication: Ctf7p/Eco1p, a cohesion establishment factor, associates with three different replication factor C complexes.
Bellaoui M, et al. (2003 Aug 15). Elg1 forms an alternative RFC complex important for DNA replication and genome integrity.
Majka J, et al. (2003 Mar 4). Yeast Rad17/Mec3/Ddc1: a sliding clamp for the DNA damage checkpoint.
Goldman GH, et al. (2004 Apr). Aspergillus nidulans as a model system to characterize the DNA damage response in eukaryotes.
Bowman GD, et al. (2004 Jun 17). Structural analysis of a eukaryotic sliding DNA clamp-clamp loader complex.
Kim J, et al. (2005). Contrasting effects of Elg1-RFC and Ctf18-RFC inactivation in the absence of fully functional RFC in fission yeast.
Bylund GO, et al. (2005 Jul). Replication protein A-directed unloading of PCNA by the Ctf18 cohesion establishment complex.
Gray FC, et al. (2009 Sep). Inactivating pentapeptide insertions in the fission yeast replication factor C subunit Rfc2 cluster near the ATP-binding site and arginine finger motif.
Van Damme P, et al. (2012 Jul 31). N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).
| Mitochondrial localization predictions | ||
|---|---|---|
| Predotar | TargetP | MitoProt |
 |
 |
 |
| Raw data
|
||
| Phobius transmembrane predictions
0 genes with posterior transmembrane prediction > 50% |
||
