FOG04658
EOG8PG4KT
EOG8R22DC

sce:MED8

Genes: 27

SGD Description
Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation


PomBase Description
mediator complex subunit Med8


References

Myers LC, et al. (1998 Jan 1). The Med proteins of yeast and their function through the RNA polymerase II carboxy-terminal domain.

Chaves RS, et al. (1999 Jan 19). Med8, a subunit of the mediator CTD complex of RNA polymerase II, directly binds to regulatory elements of SUC2 and HXK2 genes.

Moreno-Herrero F, et al. (1999 Oct 15). Analysis by atomic force microscopy of Med8 binding to cis-acting regulatory elements of the SUC2 and HXK2 genes of saccharomyces cerevisiae.

Kang JS, et al. (2001 Nov 9). The structural and functional organization of the yeast mediator complex.

Davis JA, et al. (2002 Aug). Structure of the yeast RNA polymerase II holoenzyme: Mediator conformation and polymerase interaction.

de la Cera T, et al. (2002 Jun 7). Mediator factor Med8p interacts with the hexokinase 2: implication in the glucose signalling pathway of Saccharomyces cerevisiae.

Guglielmi B, et al. (2004). A high resolution protein interaction map of the yeast Mediator complex.

Bourbon HM, et al. (2004 Jun 4). A unified nomenclature for protein subunits of mediator complexes linking transcriptional regulators to RNA polymerase II.

Nair D, et al. (2005 Oct 7). Mediator and TFIIH govern carboxyl-terminal domain-dependent transcription in yeast extracts.

Takagi Y, et al. (2005 Sep 2). Preponderance of free mediator in the yeast Saccharomyces cerevisiae.

Takagi Y, et al. (2006 Aug 4). Head module control of mediator interactions.

Takagi Y, et al. (2006 Jan 6). Mediator as a general transcription factor.

Larivière L, et al. (2006 Oct). Structure and TBP binding of the Mediator head subcomplex Med8-Med18-Med20.

Baidoobonso SM, et al. (2007 Feb 23). Med19(Rox3) regulates Intermodule interactions in the Saccharomyces cerevisiae mediator complex.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG04659
EOG8PG4KT

sce:absent

Genes: 3

AspGD Description
Ortholog(s) have RNA polymerase II core promoter proximal region sequence-specific DNA binding, RNA polymerase II transcription corepressor activity, TBP-class protein binding, structural molecule activity

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG04660
EOG8PG4KT

sce:absent

Genes: 1

 





 

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%