HOG01210

FOG03290
EOG8BNZT0
EOG8H44K8
EOG8QJQ4P
EOG8T76J9
EOG8VQ852

sce:CHA4

Genes: 18

SGD Description
DNA binding transcriptional activator; mediates serine/threonine activation of the catabolic L-serine (L-threonine) deaminase (CHA1); Zinc-finger protein with Zn[2]-Cys[6] fungal-type binuclear cluster domain

PomBase Description
transcription factor (predicted)|zn(2)-C6 fungal-type DNA-binding transcription factor, truncated

AspGD Description
Has domain(s) with predicted DNA binding, RNA polymerase II transcription factor activity, sequence-specific DNA binding, zinc ion binding activity and role in regulation of transcription, DNA-templated, transcription, DNA-templated|Has domain(s) with predicted DNA binding, RNA polymerase II transcription factor activity, sequence-specific DNA binding, zinc ion binding activity and role in regulation of transcription, DNA-templated, transcription, DNA-templated

References

Holmberg S, et al. (1996 Oct). Cha4p of Saccharomyces cerevisiae activates transcription via serine/threonine response elements.

Beltrao P, et al. (2009 Jun 16). Evolution of phosphoregulation: comparison of phosphorylation patterns across yeast species.

Bitton DA, et al. (2011 Apr). Augmented annotation of the Schizosaccharomyces pombe genome reveals additional genes required for growth and viability.

Rhind N, et al. (2011 May 20). Comparative functional genomics of the fission yeasts.

Sun LL, et al. (2013). Global analysis of fission yeast mating genes reveals new autophagy factors.

Vachon L, et al. (2013 Aug). Functional characterization of fission yeast transcription factors by overexpression analysis.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Hu W, et al. (2015 Nov 27). Bulk Segregant Analysis Reveals the Genetic Basis of a Natural Trait Variation in Fission Yeast.

Dudin O, et al. (2017 Apr). A systematic screen for morphological abnormalities during fission yeast sexual reproduction identifies a mechanism of actin aster formation for cell fusion.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt

Raw data
Phobius transmembrane predictions 14 genes with posterior transmembrane prediction > 50%

FOG03291
EOG8H44K8

sce:absent

Genes: 8

Mitochondrial localization predictions
Predotar	TargetP	MitoProt

Raw data
Phobius transmembrane predictions 5 genes with posterior transmembrane prediction > 50%

FOG03292
EOG8T76J9

sce:absent

Genes: 8

AspGD Description
Ortholog(s) have protein domain specific binding, transcription regulatory region DNA binding activity

References

Pateman JA, et al. (1967 Jul). Genetic and biochemical studies of nitrate reduction in Aspergillus nidulans.

Arst HN Jr, et al. (1969 Jun). Methylammonium resistance in Aspergillus nidulans.

Arst HN Jr, et al. (1970). Molybdate metabolism in Aspergillus nidulans. I. Mutations affecting nitrate reductase and-or xanthine dehydrogenase.

Clutterbuck AJ, et al. (1973 Jun). Gene symbols in Aspergillus nidulans.

Hankinson O, et al. (1974 Apr 25). Regulation of the pentose phosphate pathway in the fungus Aspergillus nidulans. The effect of growth with nitrate.

Davis RH, et al. (1975). Compartmentation and regulation of fungal metabolism: genetic approaches.

Hankinson O, et al. (1975 Jan). Regulation of mannitol-1-phosphate dehydrogenase in Aspergillus nidulans.

Cove DJ, et al. (1976 Jul 23). Chlorate toxicity in Aspergillus nidulans. Studies of mutants altered in nitrate assimilation.

Dunn-Coleman NS, et al. (1977 Apr 29). In vivo and in vitro studies of nitrate reductase regulation in Asperillus nidulans.

Garrett RH, et al. (1978). Nitrate assimilation in fungi.

Rand KN, et al. (1978 Apr 20). Mutations in nirA gene of Aspergillus nidulans and nitrogen metabolism.

Cove DJ, et al. (1979 Aug). Genetic studies of nitrate assimilation in Aspergillus nidulans.

Dunn-Coleman NS, et al. (1979 Mar 9). The regulation of hexokinase and phosphoglucomutase activity in Aspergillus nidulans.

Tollervey DW, et al. (1981 Sep). Mutations to constitutivity and derepression are separate and separable in a regulatory gene of Aspergillus nidulans.

Brownlee AG, et al. (1983 Sep). Nitrate uptake in Aspergillus nidulans and involvement of the third gene of the nitrate assimilation gene cluster.

Arst HN Jr, et al. (1984 Sep). Regulation of gene expression in Aspergillus nidulans.

Wiame JM, et al. (1985). Nitrogen catabolite repression in yeasts and filamentous fungi.

Davis MA, et al. (1989 Jan). Regulatory genes in Aspergillus nidulans.

Debets AJ, et al. (1990 May). Genetic analysis of Aspergillus niger: isolation of chlorate resistance mutants, their use in mitotic mapping and evidence for an eighth linkage group.

Hawker KL, et al. (1991 Apr). Heterologous expression and regulation of the Neurospora crassa nit-4 pathway-specific regulatory gene for nitrate assimilation in Aspergillus nidulans.

Daboussi MJ, et al. (1991 Dec 20). Heterologous expression of the Aspergillus nidulans regulatory gene nirA in Fusarium oxysporum.

Burger G, et al. (1991 Feb). Molecular cloning and functional characterization of the pathway-specific regulatory gene nirA, which controls nitrate assimilation in Aspergillus nidulans.

Unkles SE, et al. (1991 Jan 1). crnA encodes a nitrate transporter in Aspergillus nidulans.

Burger G, et al. (1991 Nov). nirA, the pathway-specific regulatory gene of nitrate assimilation in Aspergillus nidulans, encodes a putative GAL4-type zinc finger protein and contains four introns in highly conserved regions.

Yuan GF, et al. (1991 Nov). nit-4, a pathway-specific regulatory gene of Neurospora crassa, encodes a protein with a putative binuclear zinc DNA-binding domain.

Scazzocchio C, et al. (1992). Control of gene expression in the catabolic pathways of Aspergillus nidulans: a personal and biased account.

Hawker KL, et al. (1992 Feb). Nitrate reductase and nitrite reductase transcript levels in various mutants of Aspergillus nidulans: confirmation of autogenous regulation.

Marzluf GA, et al. (1993). Regulation of sulfur and nitrogen metabolism in filamentous fungi.

Kinghorn JR, et al. (1994). Inorganic nitrogen assimilation: molecular aspects.

Gems D, et al. (1994 Feb). An 'instant gene bank' method for gene cloning by mutant complementation.

Punt PJ, et al. (1995 Oct). The intergenic region between the divergently transcribed niiA and niaD genes of Aspergillus nidulans contains multiple NirA binding sites which act bidirectionally.

Chang PK, et al. (1996 Jun). Characterization of the Aspergillus parasiticus niaD and niiA gene cluster.

Clutterbuck AJ, et al. (1997 Jun). The validity of the Aspergillus nidulans linkage map.

Todd RB, et al. (1997 Jun). Evolution of a fungal regulatory gene family: the Zn(II)2Cys6 binuclear cluster DNA binding motif.

Strauss J, et al. (1998 Mar). The regulator of nitrate assimilation in ascomycetes is a dimer which binds a nonrepeated, asymmetrical sequence.

Snoeijers SS, et al. (1999 Jun). Transcription of the avirulence gene Avr9 of the fungal tomato pathogen Cladosporium fulvum is regulated by a GATA-type transcription factor in Aspergillus nidulans.

Muro-Pastor MI, et al. (1999 Mar 15). The GATA factor AreA is essential for chromatin remodelling in a eukaryotic bidirectional promoter.

Unkles SE, et al. (2001 Nov 15). Apparent genetic redundancy facilitates ecological plasticity for nitrate transport.

Narendja F, et al. (2002 Apr). Nitrate and the GATA factor AreA are necessary for in vivo binding of NirA, the pathway-specific transcriptional activator of Aspergillus nidulans.

Takaya N, et al. (2002 May). Transcriptional control of nitric oxide reductase gene (CYP55) in the fungal denitrifier Fusarium oxysporum.

Muro-Pastor MI, et al. (2004 Apr). A paradoxical mutant GATA factor.

Berger H, et al. (2006 Jan). The GATA factor AreA regulates localization and in vivo binding site occupancy of the nitrate activator NirA.

Caddick MX, et al. (2006 Oct). Opposing signals differentially regulate transcript stability in Aspergillus nidulans.

Bernreiter A, et al. (2007 Feb). Nuclear export of the transcription factor NirA is a regulatory checkpoint for nitrate induction in Aspergillus nidulans.

Wang Y, et al. (2008 Feb). Nitrite transport is mediated by the nitrite-specific high-affinity NitA transporter and by nitrate transporters NrtA, NrtB in Aspergillus nidulans.

Berger H, et al. (2008 Sep). Dissecting individual steps of nitrogen transcription factor cooperation in the Aspergillus nidulans nitrate cluster.

Schinko T, et al. (2010 Nov). Transcriptome analysis of nitrate assimilation in Aspergillus nidulans reveals connections to nitric oxide metabolism.

Zhou S, et al. (2012 Jan). Heme-biosynthetic porphobilinogen deaminase protects Aspergillus nidulans from nitrosative stress.

Schinko T, et al. (2013 May). Pseudo-constitutivity of nitrate-responsive genes in nitrate reductase mutants.

Scazzocchio C, et al. (2013 Sep-Oct). In praise of erroneous hypotheses.

Tudzynski B, et al. (2014). Nitrogen regulation of fungal secondary metabolism in fungi.

Gallmetzer A, et al. (2015 Jul). Reversible Oxidation of a Conserved Methionine in the Nuclear Export Sequence Determines Subcellular Distribution and Activity of the Fungal Nitrate Regulator NirA.

Marcos AT, et al. (2016 Jan). Nitric oxide synthesis by nitrate reductase is regulated during development in Aspergillus.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt

Raw data
Phobius transmembrane predictions 6 genes with posterior transmembrane prediction > 50%

FOG03293
EOG8BNZT0
EOG8T76J9

sce:absent

Genes: 3

PomBase Description
transcription factor Cha4 (predicted)

AspGD Description
Has domain(s) with predicted DNA binding, RNA polymerase II transcription factor activity, sequence-specific DNA binding, zinc ion binding activity and role in regulation of transcription, DNA-templated, transcription, DNA-templated

References

Beltrao P, et al. (2009 Jun 16). Evolution of phosphoregulation: comparison of phosphorylation patterns across yeast species.

Kaufmann I, et al. (2010 Jul). Transcriptional activation of the general amino acid permease gene per1 by the histone deacetylase Clr6 Is regulated by Oca2 kinase.

Vachon L, et al. (2013 Aug). Functional characterization of fission yeast transcription factors by overexpression analysis.

Sideri T, et al. (2014 Dec 1). Parallel profiling of fission yeast deletion mutants for proliferation and for lifespan during long-term quiescence.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt

Raw data
Phobius transmembrane predictions 3 genes with posterior transmembrane prediction > 50%

FOG03294
EOG8T76J9

sce:absent

Genes: 2

AspGD Description
Has domain(s) with predicted DNA binding, RNA polymerase II transcription factor activity, sequence-specific DNA binding, zinc ion binding activity and role in regulation of transcription, DNA-templated, transcription, DNA-templated|Has domain(s) with predicted DNA binding, zinc ion binding activity, role in transcription, DNA-templated and nucleus localization

Mitochondrial localization predictions
Predotar	TargetP	MitoProt

Raw data
Phobius transmembrane predictions 2 genes with posterior transmembrane prediction > 50%

FOG03295
EOG8T76J9

sce:absent

Genes: 2

Mitochondrial localization predictions
Predotar	TargetP	MitoProt

Raw data
Phobius transmembrane predictions 2 genes with posterior transmembrane prediction > 50%

FOG03296
EOG8T76J9

sce:absent

Genes: 3

AspGD Description
Has domain(s) with predicted DNA binding, RNA polymerase II transcription factor activity, sequence-specific DNA binding, zinc ion binding activity and role in regulation of transcription, DNA-templated, transcription, DNA-templated|Ortholog(s) have role in negative regulation of transcription from RNA polymerase II promoter, regulation of nitrogen utilization and nucleus localization

Mitochondrial localization predictions
Predotar	TargetP	MitoProt

Raw data
Phobius transmembrane predictions 2 genes with posterior transmembrane prediction > 50%

FOG03297
EOG8BNZT0

sce:absent

Genes: 2

Mitochondrial localization predictions
Predotar	TargetP	MitoProt

Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%