FOG03137
EOG873N87

sce:CDC3

Genes: 34

SGD Description
Component of the septin ring that is required for cytokinesis; septins are GTP-binding proteins that assemble with other septins into rod-like complexes that can associate with other rods to form filament polymers; septin rings at the mother-bud neck act as scaffolds for recruiting factors needed for cell division and as barriers to prevent diffusion of specific proteins between mother and daughter cells


PomBase Description
mitotic septin Spn1


AspGD Description
Ortholog(s) have role in cellular protein localization, conidiophore development, hyphal growth, mitotic cytokinesis


References

Longtine MS, et al. (1996 Feb). The septins: roles in cytokinesis and other processes.

Momany M, et al. (1997 Feb). The Aspergillus nidulans septin encoding gene, aspB, is essential for growth.

Clutterbuck AJ, et al. (1997 Jun). The validity of the Aspergillus nidulans linkage map.

Frazier JA, et al. (1998 Nov 2). Polymerization of purified yeast septins: evidence that organized filament arrays may not be required for septin function.

Johnson ES, et al. (1999 Nov 29). Cell cycle-regulated attachment of the ubiquitin-related protein SUMO to the yeast septins.

Harris SD, et al. (2001 Dec). Septum formation in Aspergillus nidulans.

Momany M, et al. (2001 Mar). Characterization of the Aspergillus nidulans septin (asp) gene family.

Takahashi Y, et al. (2001 Sep 19). A novel factor required for the SUMO1/Smt3 conjugation of yeast septins.

Momany M, et al. (2002 Dec). Polarity in filamentous fungi: establishment, maintenance and new axes.

Tang CS, et al. (2002 Jan). Phosphorylation of the septin cdc3 in g1 by the cdc28 kinase is essential for efficient septin ring disassembly.

Westfall PJ, et al. (2002 Jan). Aspergillus nidulans septin AspB plays pre- and postmitotic roles in septum, branch, and conidiophore development.

Mortensen EM, et al. (2002 Jun). Cell cycle-dependent assembly of a Gin4-septin complex.

Casamayor A, et al. (2003 Apr). Molecular dissection of a yeast septin: distinct domains are required for septin interaction, localization, and function.

Wu JQ, et al. (2003 Nov). Spatial and temporal pathway for assembly and constriction of the contractile ring in fission yeast cytokinesis.

An H, et al. (2004 Dec). Requirements of fission yeast septins for complex formation, localization, and function.

Zhou W, et al. (2004 Jul 30). Global analyses of sumoylated proteins in Saccharomyces cerevisiae. Induction of protein sumoylation by cellular stresses.

Versele M, et al. (2004 Oct). Protein-protein interactions governing septin heteropentamer assembly and septin filament organization in Saccharomyces cerevisiae.

Denison C, et al. (2005 Mar). A proteomic strategy for gaining insights into protein sumoylation in yeast.

Gruhler A, et al. (2005 Mar). Quantitative phosphoproteomics applied to the yeast pheromone signaling pathway.

Wu JQ, et al. (2005 Oct 14). Counting cytokinesis proteins globally and locally in fission yeast.

Chi A, et al. (2007 Feb 13). Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry.

Pan F, et al. (2007 Jul 1). Analysis of septins across kingdoms reveals orthology and new motifs.

Qiu W, et al. (2008 Nov). A novel septin-associated protein, Syp1p, is required for normal cell cycle-dependent septin cytoskeleton dynamics in yeast.

Shimizu M, et al. (2009 Jan). Proteomic analysis of Aspergillus nidulans cultured under hypoxic conditions.

Seiler S, et al. (2010 Dec). Conserved components, but distinct mechanisms for the placement and assembly of the cell division machinery in unicellular and filamentous ascomycetes.

Wu JQ, et al. (2010 Nov). Cooperation between the septins and the actomyosin ring and role of a cell-integrity pathway during cell division in fission yeast.

Bohnert KA, et al. (2012). Cytokinesis-based constraints on polarized cell growth in fission yeast.

Van Damme P, et al. (2012 Jul 31). N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

Hernández-Rodríguez Y, et al. (2012 Mar). The septin AspB in Aspergillus nidulans forms bars and filaments and plays roles in growth emergence and conidiation.

Fan JQ, et al. (2013 Aug). [Cnb1 involved in cytokinesis in Schizosaccharomyces pombe].

Hernández-Rodríguez Y, et al. (2014). Distinct septin heteropolymers co-exist during multicellular development in the filamentous fungus Aspergillus nidulans.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Muñoz S, et al. (2014 Aug 8). The putative exchange factor Gef3p interacts with Rho3p GTPase and the septin ring during cytokinesis in fission yeast.

Lei B, et al. (2014 Sep 15). Septin ring assembly is regulated by Spt20, a structural subunit of the SAGA complex.

Mojardín L, et al. (2015). Chromosome segregation and organization are targets of 5'-Fluorouracil in eukaryotic cells.

Wang N, et al. (2015 Jan 15). The Rho-GEF Gef3 interacts with the septin complex and activates the GTPase Rho4 during fission yeast cytokinesis.

Pérez P, et al. (2015 May). Rho4 interaction with exocyst and septins regulates cell separation in fission yeast.

Liu Y, et al. (2016 Aug 15). Roles of the novel coiled-coil protein Rng10 in septum formation during fission yeast cytokinesis.

McDonald NA, et al. (2017 Sep 15). Nanoscale architecture of the <i>Schizosaccharomyces pombe</i> contractile ring.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG03138
EOG873N87

sce:absent

Genes: 10

PomBase Description
mitotic septin Spn3


AspGD Description
Ortholog(s) have GTP binding, phosphatidylinositol-4-phosphate binding, phosphatidylinositol-5-phosphate binding, structural molecule activity


References

Momany M, et al. (2001 Mar). Characterization of the Aspergillus nidulans septin (asp) gene family.

Pan F, et al. (2007 Jul 1). Analysis of septins across kingdoms reveals orthology and new motifs.

Lindsey R, et al. (2010 Jan). Septins AspA and AspC are important for normal development and limit the emergence of new growth foci in the multicellular fungus Aspergillus nidulans.

Wartenberg D, et al. (2012 Jul 16). Proteome analysis of the farnesol-induced stress response in Aspergillus nidulans--The role of a putative dehydrin.

Hernández-Rodríguez Y, et al. (2012 Mar). The septin AspB in Aspergillus nidulans forms bars and filaments and plays roles in growth emergence and conidiation.

Hernández-Rodríguez Y, et al. (2014). Distinct septin heteropolymers co-exist during multicellular development in the filamentous fungus Aspergillus nidulans.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG03139


sce:absent

Genes: 0

 





 

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG03140
EOG873N87

sce:CDC10

Genes: 33

SGD Description
Component of the septin ring, required for cytokinesis; septins are GTP-binding proteins that assemble into rod-like hetero-oligomers that can associate to form filaments; septin rings at the mother-bud neck act as scaffolds for recruiting cell division factors and as barriers to prevent diffusion of specific proteins between mother and daughter cells; N-terminus interacts with phosphatidylinositol-4,5-bisphosphate; protein abundance increases under DNA damage stress


PomBase Description
mitotic and meiotic (sporulation) septin Spn2


AspGD Description
Ortholog(s) have role in adhesion of symbiont to host, asymmetric protein localization, chitin localization, chlamydospore formation and establishment of nucleus localization, more


References

Steensma HY, et al. (1991 May-Jun). Sequence of the CDC10 region at chromosome III of Saccharomyces cerevisiae.

DiDomenico BJ, et al. (1994 Mar). Homologs of the yeast neck filament associated genes: isolation and sequence analysis of Candida albicans CDC3 and CDC10.

Longtine MS, et al. (1996 Feb). The septins: roles in cytokinesis and other processes.

Frazier JA, et al. (1998 Nov 2). Polymerization of purified yeast septins: evidence that organized filament arrays may not be required for septin function.

Momany M, et al. (2001 Mar). Characterization of the Aspergillus nidulans septin (asp) gene family.

Mortensen EM, et al. (2002 Jun). Cell cycle-dependent assembly of a Gin4-septin complex.

Casamayor A, et al. (2003 Apr). Molecular dissection of a yeast septin: distinct domains are required for septin interaction, localization, and function.

Versele M, et al. (2004 Oct). Protein-protein interactions governing septin heteropentamer assembly and septin filament organization in Saccharomyces cerevisiae.

Chi A, et al. (2007 Feb 13). Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry.

Pan F, et al. (2007 Jul 1). Analysis of septins across kingdoms reveals orthology and new motifs.

Qiu W, et al. (2008 Nov). A novel septin-associated protein, Syp1p, is required for normal cell cycle-dependent septin cytoskeleton dynamics in yeast.

Van Damme P, et al. (2012 Jul 31). N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

Hernández-Rodríguez Y, et al. (2012 Mar). The septin AspB in Aspergillus nidulans forms bars and filaments and plays roles in growth emergence and conidiation.

Hernández-Rodríguez Y, et al. (2014). Distinct septin heteropolymers co-exist during multicellular development in the filamentous fungus Aspergillus nidulans.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG03141
EOG873N87

sce:CDC12

Genes: 33

SGD Description
Component of the septin ring that is required for cytokinesis; septins are GTP-binding proteins that assemble into rod-like hetero-oligomers that can associate with other rods to form filaments; septin rings at the mother-bud neck act as scaffolds for recruiting cell division factors and as barriers to prevent diffusion of specific proteins between mother and daughter cells


PomBase Description
mitotic septin Spn4


AspGD Description
Ortholog(s) have role in cell separation after cytokinesis, cellular protein localization, conidiophore development, hyphal growth, maintenance of cell polarity, mitotic cytokinesis, septin ring assembly


References

Cvrcková F, et al. (1995 Aug 1). Ste20-like protein kinases are required for normal localization of cell growth and for cytokinesis in budding yeast.

Longtine MS, et al. (1996 Feb). The septins: roles in cytokinesis and other processes.

Frazier JA, et al. (1998 Nov 2). Polymerization of purified yeast septins: evidence that organized filament arrays may not be required for septin function.

Mortensen EM, et al. (2002 Jun). Cell cycle-dependent assembly of a Gin4-septin complex.

Casamayor A, et al. (2003 Apr). Molecular dissection of a yeast septin: distinct domains are required for septin interaction, localization, and function.

An H, et al. (2004 Dec). Requirements of fission yeast septins for complex formation, localization, and function.

Versele M, et al. (2004 Oct). Protein-protein interactions governing septin heteropentamer assembly and septin filament organization in Saccharomyces cerevisiae.

Mendoza M, et al. (2005 Dec). The fission yeast MO25 protein functions in polar growth and cell separation.

Wu JQ, et al. (2005 Oct 14). Counting cytokinesis proteins globally and locally in fission yeast.

Jin QW, et al. (2006 Apr). A role for the septation initiation network in septum assembly revealed by genetic analysis of sid2-250 suppressors.

Qiu W, et al. (2008 Nov). A novel septin-associated protein, Syp1p, is required for normal cell cycle-dependent septin cytoskeleton dynamics in yeast.

Wu JQ, et al. (2010 Nov). Cooperation between the septins and the actomyosin ring and role of a cell-integrity pathway during cell division in fission yeast.

Van Damme P, et al. (2012 Jul 31). N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

Majumdar U, et al. (2012 Jun 1-15). Regulation of cell cycle and stress responses under nitrosative stress in Schizosaccharomyces pombe.

Pan X, et al. (2012 Nov 23). Identification of novel genes involved in DNA damage response by screening a genome-wide Schizosaccharomyces pombe deletion library.

Fan JQ, et al. (2013 Aug). [Cnb1 involved in cytokinesis in Schizosaccharomyces pombe].

Anver S, et al. (2014 Aug). Yeast X-chromosome-associated protein 5 (Xap5) functions with H2A.Z to suppress aberrant transcripts.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Lei B, et al. (2014 Sep 15). Septin ring assembly is regulated by Spt20, a structural subunit of the SAGA complex.

Pérez P, et al. (2015 May). Rho4 interaction with exocyst and septins regulates cell separation in fission yeast.

McDonald NA, et al. (2017 Sep 15). Nanoscale architecture of the <i>Schizosaccharomyces pombe</i> contractile ring.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG03142
EOG873N87

sce:CDC11;SHS1

Genes: 48

SGD Description
Component of the septin ring that is required for cytokinesis; septins are GTP-binding proteins that assemble into rod-like hetero-oligomers that can associate with other rods to form filaments; septin rings at the mother-bud neck act as scaffolds for recruiting cell division factors and as barriers to prevent diffusion of specific proteins between mother and daughter cells|Component of the septin ring that is required for cytokinesis; septins are GTP-binding proteins that assemble into rod-like hetero-oligomers that can associate with other rods to form filaments; septin rings at the mother-bud neck act as scaffolds for recruiting cell division factors and as barriers to prevent diffusion of specific proteins; undergoes sumoylation and phosphorylation during mitosis; protein abundance increases in response to DNA replication stress


References

Longtine MS, et al. (1996 Feb). The septins: roles in cytokinesis and other processes.

De Virgilio C, et al. (1996 Oct). SPR28, a sixth member of the septin gene family in Saccharomyces cerevisiae that is expressed specifically in sporulating cells.

Carroll CW, et al. (1998 Nov 2). The septins are required for the mitosis-specific activation of the Gin4 kinase.

Frazier JA, et al. (1998 Nov 2). Polymerization of purified yeast septins: evidence that organized filament arrays may not be required for septin function.

Mino A, et al. (1998 Oct 29). Shs1p: a novel member of septin that interacts with spa2p, involved in polarized growth in saccharomyces cerevisiae.

Johnson ES, et al. (1999 Nov 29). Cell cycle-regulated attachment of the ubiquitin-related protein SUMO to the yeast septins.

Okuzaki D, et al. (2001 Feb 2). Kcc4 associates with septin proteins of Saccharomyces cerevisiae.

Sudbery PE, et al. (2001 Jul). The germ tubes of Candida albicans hyphae and pseudohyphae show different patterns of septin ring localization.

Warenda AJ, et al. (2002 Aug). Septin function in Candida albicans morphogenesis.

Mortensen EM, et al. (2002 Jun). Cell cycle-dependent assembly of a Gin4-septin complex.

Casamayor A, et al. (2003 Apr). Molecular dissection of a yeast septin: distinct domains are required for septin interaction, localization, and function.

Warenda AJ, et al. (2003 Jul). Candida albicans septin mutants are defective for invasive growth and virulence.

Dobbelaere J, et al. (2003 Mar). Phosphorylation-dependent regulation of septin dynamics during the cell cycle.

Versele M, et al. (2004 Oct). Protein-protein interactions governing septin heteropentamer assembly and septin filament organization in Saccharomyces cerevisiae.

Kaneko A, et al. (2004 Sep). Tandem affinity purification of the Candida albicans septin protein complex.

Umeyama T, et al. (2005 Jan). Candida albicans protein kinase CaHsl1p regulates cell elongation and virulence.

Martin SW, et al. (2005 Jul). Cell cycle dynamics and quorum sensing in Candida albicans chlamydospores are distinct from budding and hyphal growth.

Gruhler A, et al. (2005 Mar). Quantitative phosphoproteomics applied to the yeast pheromone signaling pathway.

Chi A, et al. (2007 Feb 13). Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry.

Li CR, et al. (2007 Jun 1). Candida albicans hyphal morphogenesis occurs in Sec3p-independent and Sec3p-dependent phases separated by septin ring formation.

Sinha I, et al. (2007 Sep). Cyclin-dependent kinases control septin phosphorylation in Candida albicans hyphal development.

González-Novo A, et al. (2008 Apr). Sep7 is essential to modify septin ring dynamics and inhibit cell separation during Candida albicans hyphal growth.

Qiu W, et al. (2008 Nov). A novel septin-associated protein, Syp1p, is required for normal cell cycle-dependent septin cytoskeleton dynamics in yeast.

Zhang C, et al. (2010 Jan). A photostable green fluorescent protein variant for analysis of protein localization in Candida albicans.

Van Damme P, et al. (2012 Jul 31). N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

Li CR, et al. (2012 May 15). CDK regulates septin organization through cell-cycle-dependent phosphorylation of the Nim1-related kinase Gin4.

Badrane H, et al. (2012 Sep). Rapid redistribution of phosphatidylinositol-(4,5)-bisphosphate and septins during the Candida albicans response to caspofungin.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 2 genes with posterior transmembrane prediction > 50%

FOG03143
EOG873N87

sce:SPR3

Genes: 23

SGD Description
Sporulation-specific homolog of the CDC3/10/11/12 family of genes; septin protein involved in sporulation; regulated by ABFI; the yeast CDC3/10/11/12 family is a family of bud neck microfilament genes


References

Ozsarac N, et al. (1995 Oct 16). The SPR3 gene encodes a sporulation-specific homologue of the yeast CDC3/10/11/12 family of bud neck microfilaments and is regulated by ABFI.

Fares H, et al. (1996 Feb). Identification of a developmentally regulated septin and involvement of the septins in spore formation in Saccharomyces cerevisiae.

De Virgilio C, et al. (1996 Oct). SPR28, a sixth member of the septin gene family in Saccharomyces cerevisiae that is expressed specifically in sporulating cells.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 2 genes with posterior transmembrane prediction > 50%

FOG03144
EOG873N87

sce:SPR28

Genes: 19

SGD Description
Sporulation-specific homolog of the CDC3/10/11/12 family of genes; meiotic septin expressed at high levels during meiotic divisions and ascospore formation; the yeast CDC3/10/11/12 family is a family of bud neck microfilament genes


References

De Virgilio C, et al. (1996 Oct). SPR28, a sixth member of the septin gene family in Saccharomyces cerevisiae that is expressed specifically in sporulating cells.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG03145
EOG873N87

sce:absent

Genes: 3

PomBase Description
meiotic (sorulation) septin Spn6|meiotic septin Spn5|meiotic septin Spn7


References

Abe H, et al. (2000 Apr). Autoregulated expression of Schizosaccharomyces pombe meiosis-specific transcription factor Mei4 and a genome-wide search for its target genes.

Onishi M, et al. (2010 Apr). Role of septins in the orientation of forespore membrane extension during sporulation in fission yeast.

Stewart EV, et al. (2011 Apr 22). Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex.

Chen Z, et al. (2012 Oct). A genetic screen to discover pathways affecting cohesin function in Schizosaccharomyces pombe identifies chromatin effectors.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Sideri T, et al. (2014 Dec 1). Parallel profiling of fission yeast deletion mutants for proliferation and for lifespan during long-term quiescence.

Guo Y, et al. (2014 Jul). Large scale screening of genetic interaction with sgf73(+) in fission yeast.

Dudin O, et al. (2017 Apr). A systematic screen for morphological abnormalities during fission yeast sexual reproduction identifies a mechanism of actin aster formation for cell fusion.

Lee J, et al. (2017 Feb 20). Chromatin remodeller Fun30^Fft3 induces nucleosome disassembly to facilitate RNA polymerase II elongation.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%