FOG03129
EOG8DZ0BD

sce:PHO23

Genes: 29

SGD Description
Component of the Rpd3L histone deacetylase complex; involved in transcriptional regulation of PHO5; affects termination of snoRNAs and cryptic unstable transcripts (CUTs); C-terminus shares significant sequence identity with the human candidate tumor suppressor p33-ING1 and its isoform ING3


PomBase Description
ING family homolog Png2


References

Loewith R, et al. (2000 Jun). Three yeast proteins related to the human candidate tumor suppressor p33(ING1) are associated with histone acetyltransferase activities.

Loewith R, et al. (2001 Jun 29). Pho23 is associated with the Rpd3 histone deacetylase and is required for its normal function in regulation of gene expression and silencing in Saccharomyces cerevisiae.

Nourani A, et al. (2003 May 23). Opposite role of yeast ING family members in p53-dependent transcriptional activation.

Deutschbauer AM, et al. (2005 Dec). Quantitative trait loci mapped to single-nucleotide resolution in yeast.

Carrozza MJ, et al. (2005 Nov 10). Stable incorporation of sequence specific repressors Ash1 and Ume6 into the Rpd3L complex.

Keogh MC, et al. (2005 Nov 18). Cotranscriptional set2 methylation of histone H3 lysine 36 recruits a repressive Rpd3 complex.

Shi X, et al. (2006 Jul 6). ING2 PHD domain links histone H3 lysine 4 methylation to active gene repression.

Wendland J, et al. (2011 Dec). Genome evolution in the eremothecium clade of the Saccharomyces complex revealed by comparative genomics.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG03130
EOG8DZ0BD

sce:YNG2

Genes: 28

SGD Description
Subunit of NuA4, an essential histone acetyltransferase complex; positions Piccolo NuA4 for efficient acetylation of histone H4 or histone H2A; relocalizes to the cytosol in response to hypoxia; similar to human tumor suppressor ING1 and its isoforms ING4 and ING5


PomBase Description
ING family homolog Png1


References

Loewith R, et al. (2000 Jun). Three yeast proteins related to the human candidate tumor suppressor p33(ING1) are associated with histone acetyltransferase activities.

Nourani A, et al. (2001 Nov). Role of an ING1 growth regulator in transcriptional activation and targeted histone acetylation by the NuA4 complex.

Choy JS, et al. (2001 Nov 23). Yng2p-dependent NuA4 histone H4 acetylation activity is required for mitotic and meiotic progression.

Choy JS, et al. (2002 Dec). NuA4 subunit Yng2 function in intra-S-phase DNA damage response.

Kobor MS, et al. (2004 May). A protein complex containing the conserved Swi2/Snf2-related ATPase Swr1p deposits histone variant H2A.Z into euchromatin.

Zhang H, et al. (2004 Nov). The Yaf9 component of the SWR1 and NuA4 complexes is required for proper gene expression, histone H4 acetylation, and Htz1 replacement near telomeres.

Krogan NJ, et al. (2004 Sep 14). Regulation of chromosome stability by the histone H2A variant Htz1, the Swr1 chromatin remodeling complex, and the histone acetyltransferase NuA4.

Shi X, et al. (2006 Jul 6). ING2 PHD domain links histone H3 lysine 4 methylation to active gene repression.

Shevchenko A, et al. (2008). Chromatin Central: towards the comparative proteome by accurate mapping of the yeast proteomic environment.

Chen JQ, et al. (2010 May 21). The fission yeast inhibitor of growth (ING) protein Png1p functions in response to DNA damage.

Helmlinger D, et al. (2011 Jun 3). Tra1 has specific regulatory roles, rather than global functions, within the SAGA co-activator complex.

Zhou X, et al. (2013). A genome-wide screening of potential target genes to enhance the antifungal activity of micafungin in Schizosaccharomyces pombe.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Rallis C, et al. (2014 Feb 15). Systematic screen for mutants resistant to TORC1 inhibition in fission yeast reveals genes involved in cellular ageing and growth.

Graml V, et al. (2014 Oct 27). A genomic Multiprocess survey of machineries that control and link cell shape, microtubule organization, and cell-cycle progression.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG03131
EOG8DZ0BD

sce:absent

Genes: 10

 





 

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG03132
EOG8DZ0BD

sce:YNG1

Genes: 5

SGD Description
Subunit of the NuA3 histone acetyltransferase complex; this complex acetylates histone H3; contains PHD finger domain that interacts with methylated histone H3; shares significant sequence identity with the human candidate tumor suppressor p33-ING1 in C-terminal region


References

Howe L, et al. (2002 Jul). Yng1p modulates the activity of Sas3p as a component of the yeast NuA3 Hhistone acetyltransferase complex.

Taverna SD, et al. (2006 Dec 8). Yng1 PHD finger binding to H3 trimethylated at K4 promotes NuA3 HAT activity at K14 of H3 and transcription at a subset of targeted ORFs.

Shi X, et al. (2006 Jul 6). ING2 PHD domain links histone H3 lysine 4 methylation to active gene repression.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG03133
EOG8DZ0BD

sce:absent

Genes: 4

AspGD Description
Ortholog(s) have histone acetyltransferase activity, methylated histone binding activity

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG03134
EOG8DZ0BD

sce:absent

Genes: 3

AspGD Description
Ortholog(s) have methylated histone binding activity

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG03135
EOG8DZ0BD

sce:absent

Genes: 2

 





 

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG03136
EOG8DZ0BD

sce:absent

Genes: 3

AspGD Description
Has domain(s) with predicted zinc ion binding activity

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%