FOG03094
EOG80K6G0
sce:DRN1
Genes: 31
EOG80K6G0
sce:DRN1
Genes: 31
SGD Description
Splicing factor that modulates turnover of branched RNAs by Dbr1p; interacts with spliceosomal components and branched RNA splicing products; enhances Dbr1p debranching in vitro; conserved protein with domain organization identical from yeast to human; N-terminal homology to Dbr1p N-terminus, but Dbr1p catalytic residues not conserved; relocalizes to the cytosol in response to hypoxia
PomBase Description
CwfJ family protein, splicing factor (predicted)
AspGD Description
Ortholog(s) have nucleus localization
References
Dastidar RG, et al. (2012 Aug 29). The nuclear localization of SWI/SNF proteins is subjected to oxygen regulation.
Garrey SM, et al. (2014 Aug). A homolog of lariat-debranching enzyme modulates turnover of branched RNA.
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| Phobius transmembrane predictions
0 genes with posterior transmembrane prediction > 50% |
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FOG03095
EOG80K6G0
sce:MSL5
Genes: 30
EOG80K6G0
sce:MSL5
Genes: 30
SGD Description
Component of commitment complex; which defines first step in splicing pathway; essential protein that interacts with Mud2p and Prp40p, forming a bridge between the intron ends; also involved in nuclear retention of pre-mRNA; relocalizes to the cytosol in response to hypoxia
PomBase Description
zinc finger splicing factor Bpb1
AspGD Description
Ortholog(s) have U2-type prespliceosome, commitment complex, cytosol localization
References
Abovich N, et al. (1997 May 2). Cross-intron bridging interactions in the yeast commitment complex are conserved in mammals.
Rutz B, et al. (1999 Jun). Transient interaction of BBP/ScSF1 and Mud2 with the splicing machinery affects the kinetics of spliceosome assembly.
Rutz B, et al. (2000 Apr 17). A dual role for BBP/ScSF1 in nuclear pre-mRNA retention and splicing.
Beales M, et al. (2000 Aug). Mutations in the large subunit of U2AF disrupt pre-mRNA splicing, cell cycle progression and nuclear structure.
Huang T, et al. (2002 Oct 15). Pre-spliceosome formation in S.pombe requires a stable complex of SF1-U2AF(59)-U2AF(23).
Banerjee H, et al. (2004 Feb). The conserved RNA recognition motif 3 of U2 snRNA auxiliary factor (U2AF 65) is essential in vivo but dispensable for activity in vitro.
Kupfer DM, et al. (2004 Oct). Introns and splicing elements of five diverse fungi.
Kofler M, et al. (2005 Nov). GYF domain proteomics reveals interaction sites in known and novel target proteins.
Haraguchi N, et al. (2007 Jan 26). Mutations in the SF1-U2AF59-U2AF23 complex cause exon skipping in Schizosaccharomyces pombe.
Wilson-Grady JT, et al. (2008 Mar). Phosphoproteome analysis of fission yeast.
Beltrao P, et al. (2009 Jun 16). Evolution of phosphoregulation: comparison of phosphorylation patterns across yeast species.
Asakawa H, et al. (2010 Nov 9). Virtual breakdown of the nuclear envelope in fission yeast meiosis.
Ren L, et al. (2011 Feb 28). Systematic two-hybrid and comparative proteomic analyses reveal novel yeast pre-mRNA splicing factors connected to Prp19.
Livesay SB, et al. (2013 Nov). Structural and functional characterization of the N terminus of Schizosaccharomyces pombe Cwf10.
Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).
Sasaki-Haraguchi N, et al. (2015). Cwf16p Associating with the Nineteen Complex Ensures Ordered Exon Joining in Constitutive Pre-mRNA Splicing in Fission Yeast.
Lipp JJ, et al. (2015 Aug). SR protein kinases promote splicing of nonconsensus introns.
Swaffer MP, et al. (2016 Dec 15). CDK Substrate Phosphorylation and Ordering the Cell Cycle.
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| Phobius transmembrane predictions
0 genes with posterior transmembrane prediction > 50% |
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FOG03096
EOG805QJR
EOG80K6G0
sce:AIR2;AIR1
Genes: 28
EOG805QJR
EOG80K6G0
sce:AIR2;AIR1
Genes: 28
SGD Description
RNA-binding subunit of the TRAMP nuclear RNA surveillance complex; involved in nuclear RNA processing and degradation; involved in TRAMP complex assembly as a bridge between Mtr4p and Trf4p; stimulates the poly(A) polymerase activity of Pap2p in vitro; has 5 zinc knuckle motifs; AIR2 has a paralog, AIR1, that arose from the whole genome duplication; Air2p and Air1p have nonredundant roles in regulation of substrate specificity of the exosome|Zinc knuckle protein; involved in nuclear RNA processing and degradation as a component of the TRAMP complex; stimulates the poly(A) polymerase activity of Pap2p in vitro; AIR1 has a paralog, AIR2, that arose from the whole genome duplication; although Air1p and Air2p are homologous TRAMP subunits, they have nonredundant roles in regulation of substrate specificity of the exosome
PomBase Description
zinc knuckle TRAMP complex subunit Air1
References
Inoue K, et al. (2000 Oct 20). Novel RING finger proteins, Air1p and Air2p, interact with Hmt1p and inhibit the arginine methylation of Npl3p.
Vanácová S, et al. (2005 Jun). A new yeast poly(A) polymerase complex involved in RNA quality control.
LaCava J, et al. (2005 Jun 3). RNA degradation by the exosome is promoted by a nuclear polyadenylation complex.
Wyers F, et al. (2005 Jun 3). Cryptic pol II transcripts are degraded by a nuclear quality control pathway involving a new poly(A) polymerase.
Houseley J, et al. (2006 Feb). Yeast Trf5p is a nuclear poly(A) polymerase.
Hamill S, et al. (2010 Aug 24). Structure and function of the polymerase core of TRAMP, a RNA surveillance complex.
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| Phobius transmembrane predictions
0 genes with posterior transmembrane prediction > 50% |
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FOG03097
EOG80K6G0
sce:GIS2
Genes: 25
EOG80K6G0
sce:GIS2
Genes: 25
SGD Description
Translational activator for mRNAs with internal ribosome entry sites; associates with polysomes and binds to a specific subset of mRNAs; localizes to RNA processing bodies (P bodies) and to stress granules; may have a role in translation regulation under stress conditions; ortholog of human ZNF9/CNBP, a gene involved in myotonic dystrophy type 2
PomBase Description
translational activator, zf-CCHC type zinc finger protein (predicted)
AspGD Description
Ortholog(s) have cytosol, nucleolus localization|Ortholog(s) have mRNA binding, single-stranded DNA binding, translation regulator activity and role in cellular response to cold, cellular response to drug, cellular response to osmotic stress, positive regulation of translation
References
Xu HP, et al. (1992 Jul). A gene encoding a protein with seven zinc finger domains acts on the sexual differentiation pathways of Schizosaccharomyces pombe.
Kanoh J, et al. (1995 Sep). Schizosaccharomyces pombe zfs1+ encoding a zinc-finger protein functions in the mating pheromone recognition pathway.
Balciunas D, et al. (1999 Dec). Yeast genes GIS1-4: multicopy suppressors of the Gal- phenotype of snf1 mig1 srb8/10/11 cells.
Cullen CF, et al. (2000 Aug). A new genetic method for isolating functionally interacting genes: high plo1(+)-dependent mutants and their suppressors define genes in mitotic and septation pathways in fission yeast.
Malavazi I, et al. (2007 Oct). Transcriptome analysis of the Aspergillus nidulans AtmA (ATM, Ataxia-Telangiectasia mutated) null mutant.
Pancaldi V, et al. (2012 Apr). Predicting the fission yeast protein interaction network.
Sideri T, et al. (2014 Dec 1). Parallel profiling of fission yeast deletion mutants for proliferation and for lifespan during long-term quiescence.
Beckley JR, et al. (2015 Dec). A Degenerate Cohort of Yeast Membrane Trafficking DUBs Mediates Cell Polarity and Survival.
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| Phobius transmembrane predictions
0 genes with posterior transmembrane prediction > 50% |
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FOG03098
EOG80K6G0
EOG8JHB08
sce:absent
Genes: 4
EOG80K6G0
EOG8JHB08
sce:absent
Genes: 4
| Mitochondrial localization predictions | ||
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| Phobius transmembrane predictions
0 genes with posterior transmembrane prediction > 50% |
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FOG03099
EOG80K6G0
EOG8JHB08
sce:absent
Genes: 2
EOG80K6G0
EOG8JHB08
sce:absent
Genes: 2
| Mitochondrial localization predictions | ||
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| Phobius transmembrane predictions
0 genes with posterior transmembrane prediction > 50% |
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FOG03100
EOG80K6G0
sce:absent
Genes: 2
EOG80K6G0
sce:absent
Genes: 2
| Mitochondrial localization predictions | ||
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| Phobius transmembrane predictions
0 genes with posterior transmembrane prediction > 50% |
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FOG03101
EOG80K6G0
sce:absent
Genes: 2
EOG80K6G0
sce:absent
Genes: 2
AspGD Description
Has domain(s) with predicted nucleic acid binding, zinc ion binding activity
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| Phobius transmembrane predictions
0 genes with posterior transmembrane prediction > 50% |
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FOG03102
EOG80K6G0
sce:absent
Genes: 18
EOG80K6G0
sce:absent
Genes: 18
PomBase Description
zf-CCHC type zinc finger protein (predicted)
AspGD Description
Protein of unknown function|Protein of unknown function|Protein of unknown function|Protein of unknown function
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| Phobius transmembrane predictions
1 genes with posterior transmembrane prediction > 50% |
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