FOG03103
EOG8X3FH6

sce:DCW1

Genes: 37

SGD Description
Putative mannosidase; GPI-anchored membrane protein required for cell wall biosynthesis in bud formation;homologous to Dfg5p


PomBase Description
mannan endo-1,6-alpha-mannosidase (predicted)


AspGD Description
Ortholog(s) have role in budding cell bud growth, fungal-type cell wall biogenesis and anchored component of plasma membrane, cellular bud, endoplasmic reticulum localization|Predicted mannan endo-1,6-alpha-mannosidase: predicted role in carbohydrate catabolism


References

Kitagaki H, et al. (2002 Nov). Two homologous genes, DCW1 (YKL046c) and DFG5, are essential for cell growth and encode glycosylphosphatidylinositol (GPI)-anchored membrane proteins required for cell wall biogenesis in Saccharomyces cerevisiae.

Spreghini E, et al. (2003 Aug). Roles of Candida albicans Dfg5p and Dcw1p cell surface proteins in growth and hypha formation.

De Groot PW, et al. (2003 Jul 15). Genome-wide identification of fungal GPI proteins.

Harcus D, et al. (2004 Oct). Transcription profiling of cyclic AMP signaling in Candida albicans.

de Groot PW, et al. (2009 Mar). Comprehensive genomic analysis of cell wall genes in Aspergillus nidulans.

Singh RP, et al. (2011 Jul 15). Cap2-HAP complex is a critical transcriptional regulator that has dual but contrasting roles in regulation of iron homeostasis in Candida albicans.

Mitochondrial localization predictions
Predotar TargetP MitoProt
Raw data
Phobius transmembrane predictions
36 genes with posterior transmembrane prediction > 50%


FOG03104
EOG8X3FH6
EOG8Z34XG

sce:DFG5

Genes: 27

SGD Description
Putative mannosidase; essential glycosylphosphatidylinositol (GPI)-anchored membrane protein required for cell wall biogenesis in bud formation, involved in filamentous growth, homologous to Dcw1p


References

Kitagaki H, et al. (2002 Nov). Two homologous genes, DCW1 (YKL046c) and DFG5, are essential for cell growth and encode glycosylphosphatidylinositol (GPI)-anchored membrane proteins required for cell wall biogenesis in Saccharomyces cerevisiae.

Spreghini E, et al. (2003 Aug). Roles of Candida albicans Dfg5p and Dcw1p cell surface proteins in growth and hypha formation.

De Groot PW, et al. (2003 Jul 15). Genome-wide identification of fungal GPI proteins.

Lee SA, et al. (2003 May). An analysis of the Candida albicans genome database for soluble secreted proteins using computer-based prediction algorithms.

Bruno VM, et al. (2006 Mar). Control of the C. albicans cell wall damage response by transcriptional regulator Cas5.

Plaine A, et al. (2008 Oct). Functional analysis of Candida albicans GPI-anchored proteins: roles in cell wall integrity and caspofungin sensitivity.

Kung LA, et al. (2009). Global analysis of the glycoproteome in Saccharomyces cerevisiae reveals new roles for protein glycosylation in eukaryotes.

Yu Q, et al. (2013 Jul). The P-type ATPase Spf1 is required for endoplasmic reticulum functions and cell wall integrity in Candida albicans.

Mitochondrial localization predictions
Predotar TargetP MitoProt
Raw data
Phobius transmembrane predictions
25 genes with posterior transmembrane prediction > 50%


FOG03105
EOG8X3FH6

sce:absent

Genes: 7

PomBase Description
mannan endo-1,6-alpha-mannosidase (predicted)


AspGD Description
Predicted mannan endo-1,6-alpha-mannosidase; predicted role in carbohydrate catabolism|Predicted mannan endo-1,6-alpha-mannosidase; predicted role in carbohydrate catabolism|Has domain(s) with predicted catalytic activity, mannan endo-1,6-alpha-mannosidase activity and role in carbohydrate catabolic process|Putative endomannanase; induced by caspofungin|Glycosylphosphatidylinositol-anchored endo-mannanase


References

de Groot PW, et al. (2009 Mar). Comprehensive genomic analysis of cell wall genes in Aspergillus nidulans.

Colabardini AC, et al. (2013). Functional characterization of Aspergillus nidulans ypkA, a homologue of the mammalian kinase SGK.

Anver S, et al. (2014 Aug). Yeast X-chromosome-associated protein 5 (Xap5) functions with H2A.Z to suppress aberrant transcripts.

Dudin O, et al. (2017 Apr). A systematic screen for morphological abnormalities during fission yeast sexual reproduction identifies a mechanism of actin aster formation for cell fusion.

Mitochondrial localization predictions
Predotar TargetP MitoProt
Raw data
Phobius transmembrane predictions
7 genes with posterior transmembrane prediction > 50%


FOG03106
EOG8Z34XG

sce:absent

Genes: 5

AspGD Description
Putative alpha-1,6-mannanase


References

de Groot PW, et al. (2009 Mar). Comprehensive genomic analysis of cell wall genes in Aspergillus nidulans.

Mitochondrial localization predictions
Predotar TargetP MitoProt
Raw data
Phobius transmembrane predictions
0 genes with posterior transmembrane prediction > 50%


FOG03107
EOG8X3FH6

sce:absent

Genes: 4
 





 
Mitochondrial localization predictions
Predotar TargetP MitoProt
Raw data
Phobius transmembrane predictions
4 genes with posterior transmembrane prediction > 50%


FOG03108
EOG87D7ZD
EOG8K98ZM
EOG8X3FH6

sce:absent

Genes: 3
 





 
Mitochondrial localization predictions
Predotar TargetP MitoProt
Raw data
Phobius transmembrane predictions
3 genes with posterior transmembrane prediction > 50%


FOG03109
EOG8X3FH6

sce:absent

Genes: 2

AspGD Description
Has domain(s) with predicted catalytic activity|Has domain(s) with predicted catalytic activity

Mitochondrial localization predictions
Predotar TargetP MitoProt
Raw data
Phobius transmembrane predictions
2 genes with posterior transmembrane prediction > 50%


FOG03110
EOG8X3FH6

sce:absent

Genes: 2
 





 
Mitochondrial localization predictions
Predotar TargetP MitoProt
Raw data
Phobius transmembrane predictions
1 genes with posterior transmembrane prediction > 50%


FOG03111
EOG8Z34XG

sce:absent

Genes: 1
 





 
Mitochondrial localization predictions
Predotar TargetP MitoProt
Raw data
Phobius transmembrane predictions
0 genes with posterior transmembrane prediction > 50%


FOG03112
EOG8X3FH6

sce:absent

Genes: 4
 





 
Mitochondrial localization predictions
Predotar TargetP MitoProt
Raw data
Phobius transmembrane predictions
4 genes with posterior transmembrane prediction > 50%