FOG02930
EOG8P8D3R

sce:CDC34

Genes: 36

SGD Description
Ubiquitin-conjugating enzyme (E2); catalytic subunit of SCF ubiquitin-protein ligase complex (together with Skp1p, Rbx1p, Cdc53p, and an F-box protein) that regulates cell cycle progression by targeting key substrates for degradation; protein abundance increases in response to DNA replication stress


AspGD Description
Ortholog(s) have protein homodimerization activity, ubiquitin protein ligase activity, ubiquitin-protein transferase activity


References

Goebl MG, et al. (1988 Sep 9). The yeast cell cycle gene CDC34 encodes a ubiquitin-conjugating enzyme.

Drury LS, et al. (1997 Oct 1). The Cdc4/34/53 pathway targets Cdc6p for proteolysis in budding yeast.

Patton EE, et al. (1998 Mar 1). Cdc53 is a scaffold protein for multiple Cdc34/Skp1/F-box proteincomplexes that regulate cell division and methionine biosynthesis in yeast.

Seol JH, et al. (1999 Jun 15). Cdc53/cullin and the essential Hrt1 RING-H2 subunit of SCF define a ubiquitin ligase module that activates the E2 enzyme Cdc34.

Malavazi I, et al. (2007 Oct). Transcriptome analysis of the Aspergillus nidulans AtmA (ATM, Ataxia-Telangiectasia mutated) null mutant.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%

FOG02931
EOG8P8D3R

sce:UBC4;UBC5

Genes: 35

SGD Description
Ubiquitin-conjugating enzyme (E2); key E2 partner with Ubc1p for the anaphase-promoting complex (APC); mediates degradation of abnormal or excess proteins, including calmodulin and histone H3; regulates levels of DNA Polymerase-{alpha} to promote efficient and accurate DNA replication; interacts with many SCF ubiquitin protein ligases; component of the cellular stress response; UBC4 has a paralog, UBC5, that arose from the whole genome duplication|Ubiquitin-conjugating enzyme; mediates selective degradation of short-lived, abnormal, or excess proteins, including histone H3; central component of the cellular stress response; expression is heat inducible; protein abundance increases in response to DNA replication stress; UBC5 has a paralog, UBC4, that arose from the whole genome duplication


PomBase Description
ubiquitin conjugating enzyme E2 Ubc4/UbcP1


AspGD Description
Ortholog(s) have APC-Cdc20 complex activity, protein binding, bridging, ubiquitin binding, ubiquitin conjugating enzyme activity


References

Seufert W, et al. (1990 Feb). Ubiquitin-conjugating enzymes UBC4 and UBC5 mediate selective degradation of short-lived and abnormal proteins.

Cook WJ, et al. (1993 Dec 21). Tertiary structures of class I ubiquitin-conjugating enzymes are highly conserved: crystal structure of yeast Ubc4.

Reggiori F, et al. (2002 Feb). A transmembrane ubiquitin ligase required to sort membrane proteins into multivesicular bodies.

Williams C, et al. (2007 Aug 3). A conserved cysteine is essential for Pex4p-dependent ubiquitination of the peroxisomal import receptor Pex5p.

Starita LM, et al. (2012 Jan). Sites of ubiquitin attachment in Saccharomyces cerevisiae.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG02932
EOG8P8D3R

sce:UBC8

Genes: 34

SGD Description
Ubiquitin-conjugating enzyme that regulates gluconeogenesis; negatively regulates gluconeogenesis by mediating the glucose-induced ubiquitination of fructose-1,6-bisphosphatase (FBPase); cytoplasmic enzyme that catalyzes the ubiquitination of histones in vitro


PomBase Description
ubiquitin conjugating enzyme E2 Ubc8 (predicted)


AspGD Description
Has domain(s) with predicted acid-amino acid ligase activity


References

Qin S, et al. (1991 Aug 15). Cloning and characterization of a Saccharomyces cerevisiae gene encoding a new member of the ubiquitin-conjugating protein family.

Kaiser P, et al. (1994 Mar 25). A human ubiquitin-conjugating enzyme homologous to yeast UBC8.

Schüle T, et al. (2000 May 15). Ubc8p functions in catabolite degradation of fructose-1, 6-bisphosphatase in yeast.

Regelmann J, et al. (2003 Apr). Catabolite degradation of fructose-1,6-bisphosphatase in the yeast Saccharomyces cerevisiae: a genome-wide screen identifies eight novel GID genes and indicates the existence of two degradation pathways.

Pancaldi V, et al. (2012 Apr). Predicting the fission yeast protein interaction network.

Olsen SK, et al. (2013 Mar 7). Structure of a ubiquitin E1-E2 complex: insights to E1-E2 thioester transfer.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Beckley JR, et al. (2015 Dec). A Degenerate Cohort of Yeast Membrane Trafficking DUBs Mediates Cell Polarity and Survival.

Chen JS, et al. (2016 Sep). Discovery of genes involved in mitosis, cell division, cell wall integrity and chromosome segregation through construction of Schizosaccharomyces pombe deletion strains.

Lv Z, et al. (2017 Feb 16). S. pombe Uba1-Ubc15 Structure Reveals a Novel Regulatory Mechanism of Ubiquitin E2 Activity.

Lee J, et al. (2017 Feb 20). Chromatin remodeller Fun30^Fft3 induces nucleosome disassembly to facilitate RNA polymerase II elongation.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG02933
EOG8P8D3R

sce:RAD6

Genes: 34

SGD Description
Ubiquitin-conjugating enzyme (E2); involved in postreplication repair as a heterodimer with Rad18p, regulation of K63 polyubiquitination in response to oxidative stress, DSBR and checkpoint control as a heterodimer with Bre1p, ubiquitin-mediated N-end rule protein degradation as a heterodimer with Ubr1p, as well as endoplasmic reticulum-associated protein degradation (ERAD) with Ubr1p in the absence of canonical ER membrane ligases


PomBase Description
Rad6 homolog, ubiquitin conjugating enzyme E2 Rhp6


AspGD Description
Ortholog(s) have single-stranded DNA binding, single-stranded DNA-dependent ATPase activity, ubiquitin conjugating enzyme activity


References

Montelone BA, et al. (1981). Recombination and mutagenesis in rad6 mutants of Saccharomyces cerevisiae: evidence for multiple functions of the RAD6 gene.

Reynolds P, et al. (1985 Jan). RAD6 gene of Saccharomyces cerevisiae encodes a protein containing a tract of 13 consecutive aspartates.

Jentsch S, et al. (1987 Sep 10-16). The yeast DNA repair gene RAD6 encodes a ubiquitin-conjugating enzyme.

Sung P, et al. (1990 Apr). Mutation of cysteine-88 in the Saccharomyces cerevisiae RAD6 protein abolishes its ubiquitin-conjugating activity and its various biological functions.

Madura K, et al. (1990 Feb 25). Expression of the Saccharomyces cerevisiae DNA repair gene RAD6 that encodes a ubiquitin conjugating enzyme, increases in response to DNA damage and in meiosis but remains constant during the mitotic cell cycle.

Sung P, et al. (1991 Aug). Yeast RAD6 encoded ubiquitin conjugating enzyme mediates protein degradation dependent on the N-end-recognizing E3 enzyme.

Dohmen RJ, et al. (1991 Aug 15). The N-end rule is mediated by the UBC2(RAD6) ubiquitin-conjugating enzyme.

Watkins JF, et al. (1993 Feb). The extremely conserved amino terminus of RAD6 ubiquitin-conjugating enzyme is essential for amino-end rule-dependent protein degradation.

Bailly V, et al. (1994 Apr 1). Specific complex formation between yeast RAD6 and RAD18 proteins: a potential mechanism for targeting RAD6 ubiquitin-conjugating activity to DNA damage sites.

Feuermann M, et al. (1997 Jul). The characterization of two new clusters of duplicated genes suggests a 'Lego' organization of the yeast Saccharomyces cerevisiae chromosomes.

Huang H, et al. (1997 Nov). The ubiquitin-conjugating enzyme Rad6 (Ubc2) is required for silencing in Saccharomyces cerevisiae.

Bailly V, et al. (1997 Sep 12). Yeast DNA repair proteins Rad6 and Rad18 form a heterodimer that has ubiquitin conjugating, DNA binding, and ATP hydrolytic activities.

Worthylake DK, et al. (1998 Mar 13). Crystal structure of the Saccharomyces cerevisiae ubiquitin-conjugating enzyme Rad6 at 2.6 A resolution.

Xie Y, et al. (1999 Dec 1). The E2-E3 interaction in the N-end rule pathway: the RING-H2 finger of E3 is required for the synthesis of multiubiquitin chain.

Ulrich HD, et al. (2000 Jul 3). Two RING finger proteins mediate cooperation between ubiquitin-conjugating enzymes in DNA repair.

Leng P, et al. (2000 Mar). Rad6p represses yeast-hypha morphogenesis in the human fungal pathogen Candida albicans.

Sun ZW, et al. (2002 Jul 4). Ubiquitination of histone H2B regulates H3 methylation and gene silencing in yeast.

Hoege C, et al. (2002 Sep 12). RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO.

de Padula M, et al. (2004). The post-replication repair RAD18 and RAD6 genes are involved in the prevention of spontaneous mutations caused by 7,8-dihydro-8-oxoguanine in Saccharomyces cerevisiae.

Kao CF, et al. (2004 Jan 15). Rad6 plays a role in transcriptional activation through ubiquitylation of histone H2B.

Xiao T, et al. (2005 Jan). Histone H2B ubiquitylation is associated with elongating RNA polymerase II.

Zhang H, et al. (2005 Nov 1). The error-free component of the RAD6/RAD18 DNA damage tolerance pathway of budding yeast employs sister-strand recombination.

Wood A, et al. (2005 Nov 23). The Bur1/Bur2 complex is required for histone H2B monoubiquitination by Rad6/Bre1 and histone methylation by COMPASS.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG02934
EOG8P8D3R

sce:UBC1

Genes: 33

SGD Description
Ubiquitin-conjugating enzyme; key E2 partner with Ubc4p for the anaphase-promoting complex (APC); mediates selective degradation of short-lived and abnormal proteins; plays a role in vesicle biogenesis and ER-associated protein degradation (ERAD); component of the cellular stress response; protein abundance increases in response to DNA replication stress key E2 partner with Ubc4p for the anaphase-promoting complex (APC)


PomBase Description
ubiquitin conjugating enzyme Ubc1 (predicted)


AspGD Description
Ortholog(s) have ubiquitin-protein transferase activity


References

Seufert W, et al. (1990 Dec). UBC1 encodes a novel member of an essential subfamily of yeast ubiquitin-conjugating enzymes involved in protein degradation.

Friedlander R, et al. (2000 Jul). A regulatory link between ER-associated protein degradation and the unfolded-protein response.

Bays NW, et al. (2001 Jan). Hrd1p/Der3p is a membrane-anchored ubiquitin ligase required for ER-associated degradation.

Hamilton KS, et al. (2001 Oct). Structure of a conjugating enzyme-ubiquitin thiolester intermediate reveals a novel role for the ubiquitin tail.

Merkley N, et al. (2004 Nov 5). Solution structure of the flexible class II ubiquitin-conjugating enzyme Ubc1 provides insights for polyubiquitin chain assembly.

Starita LM, et al. (2012 Jan). Sites of ubiquitin attachment in Saccharomyces cerevisiae.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG02935
EOG8P8D3R

sce:UBC13

Genes: 33

SGD Description
E2 ubiquitin-conjugating enzyme; involved in the error-free DNA postreplication repair pathway; interacts with Mms2p to assemble ubiquitin chains at the Ub Lys-63 residue; DNA damage triggers redistribution from the cytoplasm to the nucleus


PomBase Description
ubiquitin conjugating enzyme E2 Ubc13


AspGD Description
Ortholog(s) have ubiquitin conjugating enzyme activity, ubiquitin-protein transferase activity and role in UV-damage excision repair, free ubiquitin chain polymerization, postreplication repair, protein K63-linked ubiquitination


References

Matuschewski K, et al. (1996 Feb 2). Identification of a novel family of ubiquitin-conjugating enzymes with distinct amino-terminal extensions.

VanDemark AP, et al. (2001 Jun 15). Molecular insights into polyubiquitin chain assembly: crystal structure of the Mms2/Ubc13 heterodimer.

Brown M, et al. (2002 Nov 3). Structural and functional conservation of error-free DNA postreplication repair in Schizosaccharomyces pombe.

Onishi M, et al. (2003 Aug). Isolation of suppressor mutants of phosphatidylinositol 3-phosphate 5-kinase deficient cells in Schizosaccharomyces pombe.

Goldman GH, et al. (2004 Apr). Aspergillus nidulans as a model system to characterize the DNA damage response in eukaryotes.

Frampton J, et al. (2006 Jul). Postreplication repair and PCNA modification in Schizosaccharomyces pombe.

Han TX, et al. (2010). Global fitness profiling of fission yeast deletion strains by barcode sequencing.

Coulon S, et al. (2010 Jun 16). Rad8Rad5/Mms2-Ubc13 ubiquitin ligase complex controls translesion synthesis in fission yeast.

Dolan WP, et al. (2010 May). Fission yeast Hsk1 (Cdc7) kinase is required after replication initiation for induced mutagenesis and proper response to DNA alkylation damage.

Wendland J, et al. (2011 Dec). Genome evolution in the eremothecium clade of the Saccharomyces complex revealed by comparative genomics.

Gatti L, et al. (2011 Jan 19). Ubiquitin-proteasome genes as targets for modulation of cisplatin sensitivity in fission yeast.

Vejrup-Hansen R, et al. (2011 Mar 7). Schizosaccharomyces pombe Mms1 channels repair of perturbed replication into Rhp51 independent homologous recombination.

Groocock LM, et al. (2012 Jan). The RecQ4 orthologue Hrq1 is critical for DNA interstrand cross-link repair and genome stability in fission yeast.

Starita LM, et al. (2012 Jan). Sites of ubiquitin attachment in Saccharomyces cerevisiae.

Køhler JB, et al. (2013). Concerted action of the ubiquitin-fusion degradation protein 1 (Ufd1) and Sumo-targeted ubiquitin ligases (STUbLs) in the DNA-damage response.

Fontebasso Y, et al. (2013 Dec). The conserved Fanconi anemia nuclease Fan1 and the SUMO E3 ligase Pli1 act in two novel Pso2-independent pathways of DNA interstrand crosslink repair in yeast.

Olsen SK, et al. (2013 Mar 7). Structure of a ubiquitin E1-E2 complex: insights to E1-E2 thioester transfer.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Mastro TL, et al. (2014 Dec). Increased meiotic crossovers and reduced genome stability in absence of Schizosaccharomyces pombe Rad16 (XPF).

Tapia-Alveal C, et al. (2014 Jun). H2A.Z-dependent regulation of cohesin dynamics on chromosome arms.

Liu XM, et al. (2015 Sep 17). ESCRTs Cooperate with a Selective Autophagy Receptor to Mediate Vacuolar Targeting of Soluble Cargos.

Álvarez V, et al. (2016 May 6). Orderly progression through S-phase requires dynamic ubiquitylation and deubiquitylation of PCNA.

Ranatunga NS, et al. (2016 Oct 13). Characterization of a Novel MMS-Sensitive Allele of Schizosaccharomyces pombe mcm4.

Lv Z, et al. (2017 Feb 16). S. pombe Uba1-Ubc15 Structure Reveals a Novel Regulatory Mechanism of Ubiquitin E2 Activity.

Yadav RK, et al. (2017 Jul 18). Histone H3G34R mutation causes replication stress, homologous recombination defects and genomic instability in <i>S. pombe</i>.

Daigaku Y, et al. (2017 May). PCNA ubiquitylation ensures timely completion of unperturbed DNA replication in fission yeast.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%

FOG02936
EOG8P8D3R

sce:UBC9

Genes: 33

SGD Description
SUMO-conjugating enzyme involved in the Smt3p conjugation pathway; nuclear protein required for S- and M-phase cyclin degradation and mitotic control; involved in proteolysis mediated by the anaphase-promoting complex cyclosome (APCC)


PomBase Description
SUMO conjugating enzyme E2 Hus5


AspGD Description
Ortholog(s) have SUMO transferase activity, role in hyphal growth, mitotic spindle elongation, protein sumoylation and condensed nuclear chromosome, cytosol, nuclear heterochromatin localization


References

Seufert W, et al. (1995 Jan 5). Role of a ubiquitin-conjugating enzyme in degradation of S- and M-phase cyclins.

Johnson ES, et al. (1997 Oct 24). Ubc9p is the conjugating enzyme for the ubiquitin-like protein Smt3p.

Takahashi Y, et al. (2001 Sep 19). A novel factor required for the SUMO1/Smt3 conjugation of yeast septins.

Johnson ES, et al. (2001 Sep 21). An E3-like factor that promotes SUMO conjugation to the yeast septins.

Van Damme P, et al. (2012 Jul 31). N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

Harting R, et al. (2013 Dec). Interplay of the fungal sumoylation network for control of multicellular development.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG02937
EOG8P8D3R

sce:UBC7

Genes: 31

SGD Description
Ubiquitin conjugating enzyme; involved in the ER-associated protein degradation pathway; requires Cue1p for recruitment to the ER membrane; proposed to be involved in chromatin assembly


PomBase Description
ubiquitin conjugating enzyme E2 Ubc7/UbcP3


AspGD Description
Putative ubiquitin conjugating enzyme; expression enhanced by maltose


References

Vassal A, et al. (1992 Sep 24). QRI8, a novel ubiquitin-conjugating enzyme in Saccharomyces cerevisiae.

Jungmann J, et al. (1993 Jan 28). Resistance to cadmium mediated by ubiquitin-dependent proteolysis.

Chen P, et al. (1993 Jul 30). Multiple ubiquitin-conjugating enzymes participate in the in vivo degradation of the yeast MAT alpha 2 repressor.

Yamazaki RK, et al. (1996 Feb). Bacterial expression of the Saccharomyces cerevisiae ubiquitin-conjugating enzyme Ubc7.

Biederer T, et al. (1997 Dec 5). Role of Cue1p in ubiquitination and degradation at the ER surface.

Cook WJ, et al. (1997 Feb 18). Crystal structure of a class I ubiquitin conjugating enzyme (Ubc7) from Saccharomyces cerevisiae at 2.9 angstroms resolution.

Johnson PR, et al. (1998 Jul 24). Degradation signal masking by heterodimerization of MATalpha2 and MATa1 blocks their mutual destruction by the ubiquitin-proteasome pathway.

Bays NW, et al. (2001 Jan). Hrd1p/Der3p is a membrane-anchored ubiquitin ligase required for ER-associated degradation.

Gardner RG, et al. (2001 Jul). In vivo action of the HRD ubiquitin ligase complex: mechanisms of endoplasmic reticulum quality control and sterol regulation.

Swanson R, et al. (2001 Oct 15). A conserved ubiquitin ligase of the nuclear envelope/endoplasmic reticulum that functions in both ER-associated and Matalpha2 repressor degradation.

Sims AH, et al. (2005 May). Transcriptome analysis of recombinant protein secretion by Aspergillus nidulans and the unfolded-protein response in vivo.

Neuber O, et al. (2005 Oct). Ubx2 links the Cdc48 complex to ER-associated protein degradation.

Carvalho P, et al. (2006 Jul 28). Distinct ubiquitin-ligase complexes define convergent pathways for the degradation of ER proteins.

Ravid T, et al. (2007 Apr). Autoregulation of an E2 enzyme by ubiquitin-chain assembly on its catalytic residue.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG02938
EOG8P8D3R

sce:PEX4

Genes: 30

SGD Description
Peroxisomal ubiquitin conjugating enzyme; required for peroxisomal matrix protein import and peroxisome biogenesis


PomBase Description
ubiquitin conjugating enzyme E2 Ubc16 (predicted)


References

Wiebel FF, et al. (1992 Sep 3). The Pas2 protein essential for peroxisome biogenesis is related to ubiquitin-conjugating enzymes.

Williams C, et al. (2007 Aug 3). A conserved cysteine is essential for Pex4p-dependent ubiquitination of the peroxisomal import receptor Pex5p.

Takeda K, et al. (2011). Identification of genes affecting the toxicity of anti-cancer drug bortezomib by genome-wide screening in S. pombe.

Stewart EV, et al. (2011 Apr 22). Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex.

Gatti L, et al. (2011 Jan 19). Ubiquitin-proteasome genes as targets for modulation of cisplatin sensitivity in fission yeast.

Anver S, et al. (2014 Aug). Yeast X-chromosome-associated protein 5 (Xap5) functions with H2A.Z to suppress aberrant transcripts.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 2 genes with posterior transmembrane prediction > 50%

FOG02939
EOG8P8D3R

sce:UBC11

Genes: 21

SGD Description
Ubiquitin-conjugating enzyme; most similar in sequence to Xenopus ubiquitin-conjugating enzyme E2-C, but not a true functional homolog of this E2; unlike E2-C, not required for the degradation of mitotic cyclin Clb2


PomBase Description
ubiquitin conjugating enzyme E2-C, Ubc11/UbcP4


AspGD Description
Ortholog(s) have APC-Cdc20 complex activity, ubiquitin conjugating enzyme activity


References

Townsley FM, et al. (1998 Jun 15). Functional analysis of the Saccharomyces cerevisiae UBC11 gene.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG02940
EOG8P8D3R

sce:absent

Genes: 6

PomBase Description
ubiquitin conjugating enzyme E2 Ubc14 (predicted)


AspGD Description
Putative ubiquitin conjugating enzyme; induced by growth on starch and lactate


References

Gatti L, et al. (2011 Jan 19). Ubiquitin-proteasome genes as targets for modulation of cisplatin sensitivity in fission yeast.

Olsen SK, et al. (2013 Mar 7). Structure of a ubiquitin E1-E2 complex: insights to E1-E2 thioester transfer.

Anver S, et al. (2014 Aug). Yeast X-chromosome-associated protein 5 (Xap5) functions with H2A.Z to suppress aberrant transcripts.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Gaspa L, et al. (2016). A functional genome-wide genetic screening identifies new pathways controlling the G1/S transcriptional wave.

Lv Z, et al. (2017 Feb 16). S. pombe Uba1-Ubc15 Structure Reveals a Novel Regulatory Mechanism of Ubiquitin E2 Activity.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG02941
EOG8P8D3R

sce:absent

Genes: 6

PomBase Description
ubiquitin conjugating enzyme E2 Ubc15


AspGD Description
Ortholog(s) have role in chromatin silencing at silent mating-type cassette


References

Choi ES, et al. (2002 Dec). Two ubiquitin-conjugating enzymes, Rhp6 and UbcX, regulate heterochromatin silencing in Schizosaccharomyces pombe.

Sims AH, et al. (2005 May). Transcriptome analysis of recombinant protein secretion by Aspergillus nidulans and the unfolded-protein response in vivo.

Beltrao P, et al. (2009 Jun 16). Evolution of phosphoregulation: comparison of phosphorylation patterns across yeast species.

Chen Z, et al. (2012 Oct). A genetic screen to discover pathways affecting cohesin function in Schizosaccharomyces pombe identifies chromatin effectors.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Tsutsui Y, et al. (2014 Aug). Multiple regulation of Rad51-mediated homologous recombination by fission yeast Fbh1.

Sideri T, et al. (2014 Dec 1). Parallel profiling of fission yeast deletion mutants for proliferation and for lifespan during long-term quiescence.

Lv Z, et al. (2017 Feb 16). S. pombe Uba1-Ubc15 Structure Reveals a Novel Regulatory Mechanism of Ubiquitin E2 Activity.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG02942
EOG8P8D3R

sce:absent

Genes: 6

AspGD Description
Has domain(s) with predicted acid-amino acid ligase activity

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%