FOG02172
EOG88CZBT

sce:SUR2

Genes: 33

SGD Description
Sphinganine C4-hydroxylase; catalyses the conversion of sphinganine to phytosphingosine in sphingolipid biosyntheis


PomBase Description
sphingosine hydroxylase Sur2


AspGD Description
Sphinganine hydroxylase; induced by fenpropimorph


References

Cliften P, et al. (1996 Mar). SYR2, a gene necessary for syringomycin growth inhibition of Saccharomyces cerevisiae.

Haak D, et al. (1997 Nov 21). Hydroxylation of Saccharomyces cerevisiae ceramides requires Sur2p and Scs7p.

Grilley MM, et al. (1998 May 1). Syringomycin action gene SYR2 is essential for sphingolipid 4-hydroxylation in Saccharomyces cerevisiae.

Chen D, et al. (2003 Jan). Global transcriptional responses of fission yeast to environmental stress.

Todd BL, et al. (2006 Apr). Sterol regulatory element binding protein is a principal regulator of anaerobic gene expression in fission yeast.

Li S, et al. (2006 Mar). Distinct ceramide synthases regulate polarized growth in the filamentous fungus Aspergillus nidulans.

Li S, et al. (2007 May). basA regulates cell wall organization and asexual/sexual sporulation ratio in Aspergillus nidulans.

Harris SD, et al. (2009 Mar). Morphology and development in Aspergillus nidulans: a complex puzzle.

Nakase M, et al. (2010 May 1). Mannosylinositol phosphorylceramide is a major sphingolipid component and is required for proper localization of plasma-membrane proteins in Schizosaccharomyces pombe.

Lando D, et al. (2012). The S. pombe histone H2A dioxygenase Ofd2 regulates gene expression during hypoxia.

Vacchina P, et al. (2012 Jul). Characterization of bifunctional sphingolipid Δ4-desaturases/C4-hydroxylases of trypanosomatids by liquid chromatography-electrospray tandem mass spectrometry.

Kawashima SA, et al. (2012 Jul 27). Analyzing fission yeast multidrug resistance mechanisms to develop a genetically tractable model system for chemical biology.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Healey KR, et al. (2015). Sphingolipids mediate differential echinocandin susceptibility in Candida albicans and Aspergillus nidulans.

Lipp JJ, et al. (2015 Aug). SR protein kinases promote splicing of nonconsensus introns.

Athanasopoulos A, et al. (2015 Oct 15). Characterization of AnNce102 and its role in eisosome stability and sphingolipid biosynthesis.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 33 genes with posterior transmembrane prediction > 50%