FOG02094
EOG83J9NJ

sce:PSD1

Genes: 33

Protein description
Phosphatidylserine decarboxylase of the mitochondrial inner membrane


SGD Description
Phosphatidylserine decarboxylase of the mitochondrial inner membrane; converts phosphatidylserine to phosphatidylethanolamine; regulates mitochondrial fusion and morphology by affecting lipid mixing in the mitochondrial membrane and by influencing the ratio of long to short forms of Mgm1p; partly exposed to the mitochondrial intermembrane space


PomBase Description
phosphatidylserine decarboxylase Psd1


AspGD Description
Phosphatidylserine decarboxylase


References

Carson MA, et al. (1984 May 25). Coordinate regulation of phosphatidylserine decarboxylase activity and phospholipid N-methylation in yeast.

Kuchler K, et al. (1986 Mar). Subcellular and submitochondrial localization of phospholipid-synthesizing enzymes in Saccharomyces cerevisiae.

Clancey CJ, et al. (1993 Nov 25). Cloning of a gene (PSD1) encoding phosphatidylserine decarboxylase from Saccharomyces cerevisiae by complementation of an Escherichia coli mutant.

Trotter PJ, et al. (1993 Oct 5). Phosphatidylserine decarboxylase from Saccharomyces cerevisiae. Isolation of mutants, cloning of the gene, and creation of a null allele.

Achleitner G, et al. (1995 Dec 15). Synthesis and intracellular transport of aminoglycerophospholipids in permeabilized cells of the yeast, Saccharomyces cerevisiae.

Birner R, et al. (2001 Apr). Roles of phosphatidylethanolamine and of its several biosynthetic pathways in Saccharomyces cerevisiae.

Sickmann A, et al. (2003 Nov 11). The proteome of Saccharomyces cerevisiae mitochondria.

Nebauer R, et al. (2007 Dec). The phosphatidylethanolamine level of yeast mitochondria is affected by the mitochondrial components Oxa1p and Yme1p.

Gulshan K, et al. (2008 Oct). Evidence for the bifunctional nature of mitochondrial phosphatidylserine decarboxylase: role in Pdr3-dependent retrograde regulation of PDR5 expression.

Chen YL, et al. (2010 Mar). Phosphatidylserine synthase and phosphatidylserine decarboxylase are essential for cell wall integrity and virulence in Candida albicans.

Tamura Y, et al. (2012 Dec 21). Phosphatidylethanolamine biosynthesis in mitochondria: phosphatidylserine (PS) trafficking is independent of a PS decarboxylase and intermembrane space proteins UPS1P and UPS2P.

Chan EY, et al. (2012 Nov 23). Phosphatidylserine decarboxylase 1 (Psd1) promotes mitochondrial fusion by regulating the biophysical properties of the mitochondrial membrane and alternative topogenesis of mitochondrial genome maintenance protein 1 (Mgm1).

Horvath SE, et al. (2012 Oct 26). Processing and topology of the yeast mitochondrial phosphatidylserine decarboxylase 1.

Onguka O, et al. (2015 May 15). Phosphatidylserine decarboxylase 1 autocatalysis and function does not require a mitochondrial-specific factor.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 30 genes with posterior transmembrane prediction > 50%

FOG02095
EOG83J9NJ

sce:absent

Genes: 2

Parent
ohnolog:FOG02094


PomBase Description
phosphatidylserine decarboxylase Psd2


References

Luo J, et al. (2009 May). Phosphatidylethanolamine is required for normal cell morphology and cytokinesis in the fission yeast Schizosaccharomyces pombe.

Mojardín L, et al. (2015). Chromosome segregation and organization are targets of 5'-Fluorouracil in eukaryotic cells.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%