FOG02096
EOG81JWT8

sce:CKI1

Genes: 35

Protein description
Choline kinase


SGD Description
Choline kinase; catalyzes the first step in phosphatidylcholine synthesis via the CDP-choline (Kennedy pathway); exhibits some ethanolamine kinase activity contributing to phosphatidylethanolamine synthesis via the CDP-ethanolamine pathway; CKI1 has a paralog, EKI1, that arose from the whole genome duplication


PomBase Description
choline/ethanolamine kinase Eki1 (predicted)


AspGD Description
Ortholog(s) have cytosol, nucleus localization


References

Hosaka K, et al. (1989 Feb 5). Cloning and characterization of the yeast CKI gene encoding choline kinase and its expression in Escherichia coli.

Yu Y, et al. (2002 Sep 20). Phosphorylation of Saccharomyces cerevisiae choline kinase on Ser30 and Ser85 by protein kinase A regulates phosphatidylcholine synthesis by the CDP-choline pathway.

Gruhler A, et al. (2005 Mar). Quantitative phosphoproteomics applied to the yeast pheromone signaling pathway.

Calvert ME, et al. (2008 Feb). Phosphorylation by casein kinase 2 regulates Nap1 localization and function.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 3 genes with posterior transmembrane prediction > 50%

FOG02097
EOG81JWT8

sce:EKI1

Genes: 1

SGD Description
Ethanolamine kinase; primarily responsible for phosphatidylethanolamine synthesis via the CDP-ethanolamine pathway; exhibits some choline kinase activity, thus contributing to phosphatidylcholine synthesis via the CDP-choline pathway; EKI1 has a paralog, CKI1, that arose from the whole genome duplication


References

Kim K, et al. (1999 May 21). Isolation and characterization of the Saccharomyces cerevisiae EKI1 gene encoding ethanolamine kinase.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%