FOG02092
EOG89GJ2X

sce:PSD2

Genes: 31

SGD Description
Phosphatidylserine decarboxylase of the Golgi and vacuolar membranes; converts phosphatidylserine to phosphatidylethanolamine; controls vacuolar membrane phospholipid content by regulating phospholipids in compartments that will eventually give rise to the vacuole; loss of Psd2p causes a specific reduction in vacuolar membrane PE levels while total PE levels are not significantly affected


PomBase Description
phosphatidylserine decarboxylase Psd3


AspGD Description
Phosphatidylserine decarboxylase


References

Trotter PJ, et al. (1995 Mar 17). Identification of a non-mitochondrial phosphatidylserine decarboxylase activity (PSD2) in the yeast Saccharomyces cerevisiae.

Trotter PJ, et al. (1995 Mar 17). Phosphatidylserine decarboxylase 2 of Saccharomyces cerevisiáe. Cloning and mapping of the gene, heterologous expression, and creation of the null allele.

Birner R, et al. (2001 Apr). Roles of phosphatidylethanolamine and of its several biosynthetic pathways in Saccharomyces cerevisiae.

Wu WI, et al. (2001 Mar 9). Characterization of phosphatidylserine transport to the locus of phosphatidylserine decarboxylase 2 in permeabilized yeast.

Kitamura H, et al. (2002 Sep 13). The C2 domain of phosphatidylserine decarboxylase 2 is not required for catalysis but is essential for in vivo function.

Gulshan K, et al. (2010 Feb 1). Compartment-specific synthesis of phosphatidylethanolamine is required for normal heavy metal resistance.

Chen YL, et al. (2010 Mar). Phosphatidylserine synthase and phosphatidylserine decarboxylase are essential for cell wall integrity and virulence in Candida albicans.

Riekhof WR, et al. (2014 Feb 28). An assembly of proteins and lipid domains regulates transport of phosphatidylserine to phosphatidylserine decarboxylase 2 in Saccharomyces cerevisiae.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 29 genes with posterior transmembrane prediction > 50%

FOG02093
EOG89GJ2X

sce:absent

Genes: 2

AspGD Description
Phosphatidylserine decarboxylase

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%