FOG01986
EOG8ZS7JR

sce:ERG5

Genes: 35

SGD Description
C-22 sterol desaturase; a cytochrome P450 enzyme that catalyzes the formation of the C-22(23) double bond in the sterol side chain in ergosterol biosynthesis; may be a target of azole antifungal drugs


PomBase Description
C-22 sterol desaturase Erg5


AspGD Description
C-22 sterol desaturase|C-22 sterol desaturase


References

Kelly SL, et al. (1995 Dec 18). Purification and reconstitution of activity of Saccharomyces cerevisiae P450 61, a sterol delta 22-desaturase.

Skaggs BA, et al. (1996 Feb 22). Cloning and characterization of the Saccharomyces cerevisiae C-22 sterol desaturase gene, encoding a second cytochrome P-450 involved in ergosterol biosynthesis.

Peng J, et al. (2003 Aug). A proteomics approach to understanding protein ubiquitination.

Mo C, et al. (2005 Sep). Erg28p is a key protein in the yeast sterol biosynthetic enzyme complex.

Kelly DE, et al. (2009 Mar). The CYPome (Cytochrome P450 complement) of Aspergillus nidulans.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 35 genes with posterior transmembrane prediction > 50%