FOG01984
EOG8HHMKQ

sce:ERG3

Genes: 36

SGD Description
C-5 sterol desaturase; glycoprotein that catalyzes the introduction of a C-5(6) double bond into episterol, a precursor in ergosterol biosynthesis; mutants are viable, but cannot grow on non-fermentable carbon sources; substrate of the HRD ubiquitin ligase


PomBase Description
C-5 sterol desaturase Erg31


AspGD Description
C-5 sterol desaturase; induced by fenpropimorph|C-5 sterol desaturase


References

Arthington BA, et al. (1991 Jun 15). Cloning, disruption and sequence of the gene encoding yeast C-5 sterol desaturase.

Taguchi N, et al. (1994 Feb). Identification and analysis of the Saccharomyces cerevisiae SYR1 gene reveals that ergosterol is involved in the action of syringomycin.

Geber A, et al. (1995 Dec). Deletion of the Candida glabrata ERG3 and ERG11 genes: effect on cell viability, cell growth, sterol composition, and antifungal susceptibility.

Peng J, et al. (2003 Aug). A proteomics approach to understanding protein ubiquitination.

Hughes AL, et al. (2005 Mar 25). SREBP pathway responds to sterols and functions as an oxygen sensor in fission yeast.

Mo C, et al. (2005 Sep). Erg28p is a key protein in the yeast sterol biosynthetic enzyme complex.

Todd BL, et al. (2006 Apr). Sterol regulatory element binding protein is a principal regulator of anaerobic gene expression in fission yeast.

Kim H, et al. (2006 Jul 25). A global topology map of the Saccharomyces cerevisiae membrane proteome.

Rodríguez-Gabriel MA, et al. (2006 Sep). Upf1, an RNA helicase required for nonsense-mediated mRNA decay, modulates the transcriptional response to oxidative stress in fission yeast.

Iwaki T, et al. (2008 Mar). Multiple functions of ergosterol in the fission yeast Schizosaccharomyces pombe.

Fang Y, et al. (2009 Jun). Pleiotropic phenotypes caused by an opal nonsense mutation in an essential gene encoding HMG-CoA reductase in fission yeast.

Lando D, et al. (2012). The S. pombe histone H2A dioxygenase Ofd2 regulates gene expression during hypoxia.

Takami T, et al. (2012). A genetic and pharmacological analysis of isoprenoid pathway by LC-MS/MS in fission yeast.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 36 genes with posterior transmembrane prediction > 50%

FOG01985
EOG8HHMKQ

sce:absent

Genes: 1

Parent
paralog:FOG01984


PomBase Description
C-5 sterol desaturase Erg32

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%