FOG01973
EOG8N2Z3X

sce:ERG7

Genes: 35

SGD Description
Lanosterol synthase; an essential enzyme that catalyzes the cyclization of squalene 2,3-epoxide, a step in ergosterol biosynthesis


PomBase Description
lanosterol synthase Erg7


AspGD Description
2,3-oxidosqualene-lanosterol cyclase|Ortholog(s) have cytosol localization|2,3-oxidosqualene-lanosterol cyclase


References

Balliano G, et al. (1992 Feb 14). Characterization and partial purification of squalene-2,3-oxide cyclase from Saccharomyces cerevisiae.

Roessner CA, et al. (1993 May 15). Sequence of the Candida albicans erg7 gene.

Shi Z, et al. (1994 Jul 19). Isolation and characterization of the gene encoding 2,3-oxidosqualene-lanosterol cyclase from Saccharomyces cerevisiae.

Corey EJ, et al. (1994 Mar 15). Molecular cloning, characterization, and overexpression of ERG7, the Saccharomyces cerevisiae gene encoding lanosterol synthase.

Milla P, et al. (2002 Jan 25). Yeast oxidosqualene cyclase (Erg7p) is a major component of lipid particles.

Mo C, et al. (2003 Jul 4). In yeast sterol biosynthesis the 3-keto reductase protein (Erg27p) is required for oxidosqualene cyclase (Erg7p) activity.

Oliaro-Bosso S, et al. (2005 Dec). Access of the substrate to the active site of yeast oxidosqualene cyclase: an inhibition and site-directed mutagenesis approach.

Malavazi I, et al. (2007 Oct). Transcriptome analysis of the Aspergillus nidulans AtmA (ATM, Ataxia-Telangiectasia mutated) null mutant.

Van Damme P, et al. (2012 Jul 31). N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 15 genes with posterior transmembrane prediction > 50%