FOG01785
EOG898SFM

sce:ATH1

Genes: 26

SGD Description
Acid trehalase required for utilization of extracellular trehalose; involved in intracellular trehalose degradation during growth recovery after saline stress


AspGD Description
Putative alpha,alpha-trehalase; expression repressed by tunicamycin and DTT


References

Arnold WN, et al. (1975). Trehalose and glycogen levels during the initial stages of growth of Candida albicans.

Molloy C, et al. (1995 Sep). Differential extraction of N-acetylglucosaminidase and trehalase from the cell envelope of Candida albicans.

Destruelle M, et al. (1995 Sep 15). Isolation and characterization of a novel yeast gene, ATH1, that is required for vacuolar acid trehalase activity.

Alizadeh P, et al. (1996 Aug 12). Purification and biochemical characterization of the ATH1 gene product, vacuolar acid trehalase, from Saccharomyces cerevisiae.

d'Enfert C, et al. (1997 Apr). Molecular characterization of the Aspergillus nidulans treA gene encoding an acid trehalase required for growth on trehalose.

Muthuvijayan V, et al. (2004). In silico reconstruction of nutrient-sensing signal transduction pathways in Aspergillus nidulans.

Pedreño Y, et al. (2004 Sep 24). The ATC1 gene encodes a cell wall-linked acid trehalase required for growth on trehalose in Candida albicans.

Pedreño Y, et al. (2007 May). Disruption of the Candida albicans ATC1 gene encoding a cell-linked acid trehalase decreases hypha formation and infectivity without affecting resistance to oxidative stress.

Ni M, et al. (2007 Oct 3). A novel regulator couples sporogenesis and trehalose biogenesis in Aspergillus nidulans.

Sánchez-Fresneda R, et al. (2009 May 22). On the biochemical classification of yeast trehalases: Candida albicans contains two enzymes with mixed features of neutral and acid trehalase activities.

Hagiwara D, et al. (2009 Nov). Transcriptional profiling for Aspergillusnidulans HogA MAPK signaling pathway in response to fludioxonil and osmotic stress.

Singh RP, et al. (2011 Jul 15). Cap2-HAP complex is a critical transcriptional regulator that has dual but contrasting roles in regulation of iron homeostasis in Candida albicans.

Saykhedkar S, et al. (2012 Jul 26). A time course analysis of the extracellular proteome of Aspergillus nidulans growing on sorghum stover.

Szilágyi M, et al. (2013 Jan). Transcriptome changes initiated by carbon starvation in Aspergillus nidulans.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 10 genes with posterior transmembrane prediction > 50%