FOG01576
EOG8BCC3X

sce:URA7;URA8

Genes: 36

SGD Description
Major CTP synthase isozyme (see also URA8); catalyzes the ATP-dependent transfer of the amide nitrogen from glutamine to UTP, forming CTP, the final step in de novo biosynthesis of pyrimidines; involved in phospholipid biosynthesis; capable of forming cytoplasmic filaments termed cytoophidium, especially during conditions of glucose depletion; URA7 has a paralog, URA8, that arose from the whole genome duplication|Minor CTP synthase isozyme (see also URA7); catalyzes the ATP-dependent transfer of the amide nitrogen from glutamine to UTP, forming CTP, the final step in de novo biosynthesis of pyrimidines; involved in phospholipid biosynthesis; capable of forming cytoplasmic filaments termed cytoophidium, especially during conditions of glucose depletion; URA8 has a paralog, URA7, that arose from the whole genome duplication


PomBase Description
CTP synthase Cts1 (predicted)


AspGD Description
CTP synthase


References

Ozier-Kalogeropoulos O, et al. (1991 Dec). Cloning, sequencing and characterization of the Saccharomyces cerevisiae URA7 gene encoding CTP synthetase.

Ozier-Kalogeropoulos O, et al. (1994 Feb). Use of synthetic lethal mutants to clone and characterize a novel CTP synthetase gene in Saccharomyces cerevisiae.

Yang WL, et al. (1994 Sep 6). Purification and characterization of CTP synthetase, the product of the URA7 gene in Saccharomyces cerevisiae.

Nadkarni AK, et al. (1995 Oct 20). Differential biochemical regulation of the URA7- and URA8-encoded CTP synthetases from Saccharomyces cerevisiae.

Ostrander DB, et al. (1998 Jul 24). Effect of CTP synthetase regulation by CTP on phospholipid synthesis in Saccharomyces cerevisiae.

Peng J, et al. (2003 Aug). A proteomics approach to understanding protein ubiquitination.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%