FOG01575
EOG8XWDFZ

sce:CDC21

Genes: 33

SGD Description
Thymidylate synthase; required for de novo biosynthesis of pyrimidine deoxyribonucleotides; expression is induced at G1/S


PomBase Description
thymidylate synthase/ flavoprotein fusion protein Hal3


AspGD Description
Thymidylate synthase


References

Hartwell LH, et al. (1973 Jun). Genetic Control of the Cell Division Cycle in Yeast: V. Genetic Analysis of cdc Mutants.

Hartwell LH, et al. (1973 Sep). Three additional genes required for deoxyribonucleic acid synthesis in Saccharomyces cerevisiae.

Bisson L, et al. (1977 Oct). Thymidine 5'-monophosphate-requiring mutants of Saccharomyces cerevisiae are deficient in thymidylate synthetase.

Bisson LF, et al. (1981 Dec 10). Thymidylate synthetase from Saccharomyces cerevisiae. Purification and enzymic properties.

Taylor GR, et al. (1982 Apr). Isolation of the thymidylate synthetase gene (TMP1) by complementation in Saccharomyces cerevisiae.

Johnston LH, et al. (1986 Aug). The expression in meiosis of genes which are transcribed periodically in the mitotic cell cycle of budding yeast.

McIntosh EM, et al. (1986 Sep). Transcription of genes encoding enzymes involved in DNA synthesis during the cell cycle of Saccharomyces cerevisiae.

Taylor GR, et al. (1987 Apr 15). Molecular characterization of the cell cycle-regulated thymidylate synthase gene of Saccharomyces cerevisiae.

McIntosh EM, et al. (1988 Nov). Transcriptional regulation of the cell cycle-dependent thymidylate synthase gene of Saccharomyces cerevisiae.

Singer SC, et al. (1989 Mar). Cloning, purification, and properties of Candida albicans thymidylate synthase.

Moll T, et al. (1992). SWI6 is a regulatory subunit of two different cell cycle START-dependent transcription factors in Saccharomyces cerevisiae.

Dirick L, et al. (1992 Jun 11). A central role for SWI6 in modulating cell cycle Start-specific transcription in yeast.

Verma R, et al. (1992 Oct 15). Regulation of the yeast DNA replication genes through the Mlu I cell cycle box is dependent on SWI6.

Poon PP, et al. (1994 Mar 18). Thymidylate synthase is localized to the nuclear periphery in the yeast Saccharomyces cerevisiae.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 3 genes with posterior transmembrane prediction > 50%