FOG00983
EOG8V15FQ
GDH2
sce:GDH2

Genes: 33

Protein description
NADH glutatmate dehydrogenase, invovled in glutamate catabolism


SGD Description
NAD(+)-dependent glutamate dehydrogenase; degrades glutamate to ammonia and alpha-ketoglutarate; expression sensitive to nitrogen catabolite repression and intracellular ammonia levels; genetically interacts with GDH3 by suppressing stress-induced apoptosis


PomBase Description
NAD-dependent glutamate dehydrogenase Gdh2 (predicted)


AspGD Description
NAD+-dependent glutamate dehydrogenase


References

Pateman JA, et al. (1969 Dec). Regulation of synthesis of glutamate dehydrogenase and glutamine synthetase in micro-organisms.

Cohen BL, et al. (1973 Dec). Regulation of intracellular and extracellular neutral and alkaline proteases in Aspergillus nidulans.

Kinghorn JR, et al. (1973 Sep). NAD and NADP l-glutamate dehydrogenase activity and ammonium regulation in Aspergillus nidulans.

Hynes MJ, et al. (1974 Mar). The effects of carbon source on glutamate dehydrogenase activities in Aspergillus nidulans.

Arst HN Jr, et al. (1975). A mutant of Aspergillus nidulans defective in NAD-linked glutamate dehydrogenase.

Kinghorn JR, et al. (1976 Jan). Mutants of Aspergillus nidulans lacking nicotinamide adenine dinucleotide-specific glutamate dehydrogenase.

Arst HN Jr, et al. (1976 Jul 15). Integrator gene in Aspergillus nidulans.

Kelly JM, et al. (1981 Apr). The regulation of phosphoenolpyruvate carboxykinase and the NADP-linked malic enzyme in Aspergillus nidulans.

Osmani SA, et al. (1983 Jul 1). The sub-cellular localisation of pyruvate carboxylase and of some other enzymes in Aspergillus nidulans.

Stevens L, et al. (1989 Jan 15). Purification and characterisation of NAD-glutamate dehydrogenase from Aspergillus nidulans.

Miller SM, et al. (1991 Dec). Role of the complex upstream region of the GDH2 gene in nitrogen regulation of the NAD-linked glutamate dehydrogenase in Saccharomyces cerevisiae.

Boles E, et al. (1993 Oct 1). The role of the NAD-dependent glutamate dehydrogenase in restoring growth on glucose of a Saccharomyces cerevisiae phosphoglucose isomerase mutant.

Clutterbuck AJ, et al. (1997 Jun). The validity of the Aspergillus nidulans linkage map.

Davis MA, et al. (2005 Jul). Amino acid catabolism by an areA-regulated gene encoding an L-amino acid oxidase with broad substrate specificity in Aspergillus nidulans.

Salazar M, et al. (2009 Dec). Uncovering transcriptional regulation of glycerol metabolism in Aspergilli through genome-wide gene expression data analysis.

Masuo S, et al. (2010 Dec). Global gene expression analysis of Aspergillus nidulans reveals metabolic shift and transcription suppression under hypoxia.

Breitkreutz A, et al. (2010 May 21). A global protein kinase and phosphatase interaction network in yeast.

Stewart EV, et al. (2011 Apr 22). Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex.

Van Damme P, et al. (2012 Jul 31). N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

Chen Z, et al. (2012 Oct). A genetic screen to discover pathways affecting cohesin function in Schizosaccharomyces pombe identifies chromatin effectors.

Anver S, et al. (2014 Aug). Yeast X-chromosome-associated protein 5 (Xap5) functions with H2A.Z to suppress aberrant transcripts.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Mathiassen SG, et al. (2015 Aug 21). A Two-step Protein Quality Control Pathway for a Misfolded DJ-1 Variant in Fission Yeast.

Beckley JR, et al. (2015 Dec). A Degenerate Cohort of Yeast Membrane Trafficking DUBs Mediates Cell Polarity and Survival.

Dudin O, et al. (2017 Apr). A systematic screen for morphological abnormalities during fission yeast sexual reproduction identifies a mechanism of actin aster formation for cell fusion.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%