FOG00984
EOG88CZBN

sce:GLN1

Genes: 35

SGD Description
Glutamine synthetase (GS); synthesizes glutamine from glutamate and ammonia; with Glt1p, forms the secondary pathway for glutamate biosynthesis from ammonia; expression regulated by nitrogen source and by amino acid limitation; forms filaments of back-to-back stacks of cylindrical homo-decamers at low pH, leading to enzymatic inactivation and storage during states of advanced cellular starvation; relocalizes from nucleus to cytoplasmic foci upon DNA replication stress


PomBase Description
glutamate-ammonia ligase Gln1


AspGD Description
Glutamine synthetase; induced by growth on starch and lactate


References

Kim KH, et al. (1988 Jan 15). Sequence of peptides from Saccharomyces cerevisiae glutamine synthetase. N-terminal peptide and ATP-binding domain.

Minehart PL, et al. (1992 Mar). Sequence of the GLN1 gene of Saccharomyces cerevisiae: role of the upstream region in regulation of glutamine synthetase expression.

Garrels JI, et al. (1997 Aug). Proteome studies of Saccharomyces cerevisiae: identification and characterization of abundant proteins.

Peng J, et al. (2003 Aug). A proteomics approach to understanding protein ubiquitination.

Hitchcock AL, et al. (2003 Oct 28). A subset of membrane-associated proteins is ubiquitinated in response to mutations in the endoplasmic reticulum degradation machinery.

Gruhler A, et al. (2005 Mar). Quantitative phosphoproteomics applied to the yeast pheromone signaling pathway.

Goffrini P, et al. (2007 Mar). A respiratory-deficient mutation associated with high salt sensitivity in Kluyveromyces lactis.

Starita LM, et al. (2012 Jan). Sites of ubiquitin attachment in Saccharomyces cerevisiae.

Van Damme P, et al. (2012 Jul 31). N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%