FOG00254
EOG808KPT

sce:RPO21

Genes: 33

SGD Description
RNA polymerase II largest subunit B220; part of central core; phosphorylation of C-terminal heptapeptide repeat domain regulates association with transcription and splicing factors; similar to bacterial beta-prime


PomBase Description
RNA polymerase II large subunit Rpb1


AspGD Description
DNA-directed RNA polymerase


References

Allison LA, et al. (1985 Sep). Extensive homology among the largest subunits of eukaryotic and prokaryotic RNA polymerases.

West ML, et al. (1995 Aug). Construction and analysis of yeast RNA polymerase II CTD deletion and substitution mutations.

Cronan JE Jr, et al. (1995 Aug 1). The gene encoding the biotin-apoprotein ligase of Saccharomyces cerevisiae.

Hengartner CJ, et al. (1998 Jul). Temporal regulation of RNA polymerase II by Srb10 and Kin28 cyclin-dependent kinases.

Kobor MS, et al. (1999 Jul). An unusual eukaryotic protein phosphatase required for transcription by RNA polymerase II and CTD dephosphorylation in S. cerevisiae.

Morris DP, et al. (1999 Oct 29). Phospho-carboxyl-terminal domain binding and the role of a prolyl isomerase in pre-mRNA 3'-End formation.

Murray S, et al. (2001 Jul). Phosphorylation of the RNA polymerase II carboxy-terminal domain by the Bur1 cyclin-dependent kinase.

Cramer P, et al. (2001 Jun 8). Structural basis of transcription: RNA polymerase II at 2.8 angstrom resolution.

Gnatt AL, et al. (2001 Jun 8). Structural basis of transcription: an RNA polymerase II elongation complex at 3.3 A resolution.

Bushnell DA, et al. (2002 Feb 5). Structural basis of transcription: alpha-amanitin-RNA polymerase II cocrystal at 2.8 A resolution.

Kettenberger H, et al. (2003 Aug 8). Architecture of the RNA polymerase II-TFIIS complex and implications for mRNA cleavage.

Armache KJ, et al. (2003 Jun 10). Architecture of initiation-competent 12-subunit RNA polymerase II.

Bushnell DA, et al. (2003 Jun 10). Complete, 12-subunit RNA polymerase II at 4.1-A resolution: implications for the initiation of transcription.

Chung WH, et al. (2003 Oct). RNA polymerase II/TFIIF structure and conserved organization of the initiation complex.

Cohen TJ, et al. (2003 Oct). Ask10p mediates the oxidative stress-induced destruction of the Saccharomyces cerevisiae C-type cyclin Ume3p/Srb11p.

Hitchcock AL, et al. (2003 Oct 28). A subset of membrane-associated proteins is ubiquitinated in response to mutations in the endoplasmic reticulum degradation machinery.

Diezmann S, et al. (2004 Dec). Phylogeny and evolution of medical species of Candida and related taxa: a multigenic analysis.

Kettenberger H, et al. (2004 Dec 22). Complete RNA polymerase II elongation complex structure and its interactions with NTP and TFIIS.

Bushnell DA, et al. (2004 Feb 13). Structural basis of transcription: an RNA polymerase II-TFIIB cocrystal at 4.5 Angstroms.

Jones JC, et al. (2004 Jun 11). C-terminal repeat domain kinase I phosphorylates Ser2 and Ser5 of RNA polymerase II C-terminal domain repeats.

Westover KD, et al. (2004 Nov 12). Structural basis of transcription: nucleotide selection by rotation in the RNA polymerase II active center.

Kim M, et al. (2004 Nov 25). The yeast Rat1 exonuclease promotes transcription termination by RNA polymerase II.

Armache KJ, et al. (2005 Feb 25). Structures of complete RNA polymerase II and its subcomplex, Rpb4/7.

Kettenberger H, et al. (2006 Jan). Structure of an RNA polymerase II-RNA inhibitor complex elucidates transcription regulation by noncoding RNAs.

Meyer PA, et al. (2006 Jun). Phasing RNA polymerase II using intrinsically bound Zn atoms: an updated structural model.

Shen Z, et al. (2010 Sep 1). Cotranscriptional recruitment of She2p by RNA pol II elongation factor Spt4-Spt5/DSIF promotes mRNA localization to the yeast bud.

Starita LM, et al. (2012 Jan). Sites of ubiquitin attachment in Saccharomyces cerevisiae.

Sainsbury S, et al. (2013 Jan 17). Structure and function of the initially transcribing RNA polymerase II-TFIIB complex.

Plaschka C, et al. (2015 Feb 19). Architecture of the RNA polymerase II-Mediator core initiation complex.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%

FOG00255
EOG808KPT

sce:RPO31

Genes: 33

Protein description
RNA polymerase


SGD Description
RNA polymerase III largest subunit C160; part of core enzyme; similar to bacterial beta-prime subunit and to RPA190 and RPO21


PomBase Description
DNA-directed RNA polymerase III complex large subunit Rpc1 (predicted)


AspGD Description
DNA-directed RNA polymerase


References

Allison LA, et al. (1985 Sep). Extensive homology among the largest subunits of eukaryotic and prokaryotic RNA polymerases.

Hermann-Le Denmat S, et al. (1994 May). Suppression of yeast RNA polymerase III mutations by FHL1, a gene coding for a fork head protein involved in rRNA processing.

Thuillier V, et al. (1996 Feb 1). Mutations in the alpha-amanitin conserved domain of the largest subunit of yeast RNA polymerase III affect pausing, RNA cleavage and transcriptional transitions.

Chédin S, et al. (1998). The yeast RNA polymerase III transcription machinery: a paradigm for eukaryotic gene activation.

Jasiak AJ, et al. (2006 Jul 7). Structural biology of RNA polymerase III: subcomplex C17/25 X-ray structure and 11 subunit enzyme model.

Malavazi I, et al. (2007 Oct). Transcriptome analysis of the Aspergillus nidulans AtmA (ATM, Ataxia-Telangiectasia mutated) null mutant.

Wendland J, et al. (2011 Dec). Genome evolution in the eremothecium clade of the Saccharomyces complex revealed by comparative genomics.

Van Damme P, et al. (2012 Jul 31). N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG00257
EOG808KPT

sce:absent

Genes: 1

Parent
paralog:FOG00254

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%