FOG00252
EOG81NS7C

sce:RPA12

Genes: 32

Protein description
RNA polymerase


SGD Description
RNA polymerase I subunit A12.2; contains two zinc binding domains, and the N terminal domain is responsible for anchoring to the RNA pol I complex


PomBase Description
DNA-directed RNA polymerase complex I subunit Rpa12


AspGD Description
DNA-directed RNA polymerase


References

Nogi Y, et al. (1993 Jan). Gene RRN4 in Saccharomyces cerevisiae encodes the A12.2 subunit of RNA polymerase I and is essential only at high temperatures.

Bischler N, et al. (2002 Aug 1). Localization of the yeast RNA polymerase I-specific subunits.

Van Mullem V, et al. (2002 Mar). Rpa12p, a conserved RNA polymerase I subunit with two functional domains.

Peyroche G, et al. (2002 Nov 12). The A14-A43 heterodimer subunit in yeast RNA pol I and their relationship to Rpb4-Rpb7 pol II subunits.

Prescott EM, et al. (2004 Apr 20). Transcriptional termination by RNA polymerase I requires the small subunit Rpa12p.

Kuhn CD, et al. (2007 Dec 28). Functional architecture of RNA polymerase I.

Engel C, et al. (2013 Oct 31). RNA polymerase I structure and transcription regulation.

Fernández-Tornero C, et al. (2013 Oct 31). Crystal structure of the 14-subunit RNA polymerase I.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG00253
EOG81NS7C

sce:RPC11

Genes: 33

Protein description
RNA polymerase


SGD Description
RNA polymerase III subunit C11; mediates pol III RNA cleavage activity and is important for termination of transcription; homologous to TFIIS


PomBase Description
DNA-directed RNA polymerase III complex subunit Rpc11


AspGD Description
Ortholog(s) have RNA polymerase III activity and role in tRNA 3'-trailer cleavage, tRNA transcription from RNA polymerase III promoter, termination of RNA polymerase III transcription


References

Chédin S, et al. (1998). The yeast RNA polymerase III transcription machinery: a paradigm for eukaryotic gene activation.

Chédin S, et al. (1998 Dec 15). The RNA cleavage activity of RNA polymerase III is mediated by an essential TFIIS-like subunit and is important for transcription termination.

Zhang Z, et al. (2005). Mapping of transcription start sites in Saccharomyces cerevisiae using 5' SAGE.

Huang Y, et al. (2005 Jan). Mutations in the RNA polymerase III subunit Rpc11p that decrease RNA 3' cleavage activity increase 3'-terminal oligo(U) length and La-dependent tRNA processing.

Proshkina GM, et al. (2006). Ancient origin, functional conservation and fast evolution of DNA-dependent RNA polymerase III.

Landrieux E, et al. (2006 Jan 11). A subcomplex of RNA polymerase III subunits involved in transcription termination and reinitiation.

Yee NS, et al. (2007 Nov). Mutation of RNA Pol III subunit rpc2/polr3b Leads to Deficiency of Subunit Rpc11 and disrupts zebrafish digestive development.

Legros P, et al. (2014 Nov). RNA processing factors Swd2.2 and Sen1 antagonize RNA Pol III-dependent transcription and the localization of condensin at Pol III genes.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%