FOG00219
EOG8NP5JD

sce:REV3

Genes: 33

Protein description
DNA polymerase zeta


SGD Description
Catalytic subunit of DNA polymerase zeta; involved in translesion synthesis during post-replication repair; required for mutagenesis induced by DNA damage; involved in double-strand break repair; forms a complex with Rev7p, Pol31p and Pol32p


PomBase Description
DNA polymerase zeta catalytic subunit Rev3 (predicted)


AspGD Description
DNA-directed DNA polymerase


References

Morrison A, et al. (1989 Oct). REV3, a Saccharomyces cerevisiae gene whose function is required for induced mutagenesis, is predicted to encode a nonessential DNA polymerase.

Nelson JR, et al. (1996 Jun 14). Thymine-thymine dimer bypass by yeast DNA polymerase zeta.

Haracska L, et al. (2001 Apr 15). Roles of yeast DNA polymerases delta and zeta and of Rev1 in the bypass of abasic sites.

Zhang H, et al. (2006 Apr). Saccharomyces cerevisiae polymerase zeta functions in mitochondria.

Netz DJ, et al. (2011 Nov 27). Eukaryotic DNA polymerases require an iron-sulfur cluster for the formation of active complexes.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 4 genes with posterior transmembrane prediction > 50%