FOG00218
EOG876HF0

sce:POL2

Genes: 34

Protein description
DNA polymerase II, epsilon


SGD Description
Catalytic subunit of DNA polymerase (II) epsilon; a chromosomal DNA replication polymerase that exhibits processivity and proofreading exonuclease activity; participates in leading-strand synthesis during DNA replication; also involved in DNA synthesis during DNA repair; interacts extensively with Mrc1p


PomBase Description
DNA polymerase epsilon catalytic subunit Pol2


AspGD Description
DNA-directed DNA polymerase


References

Morrison A, et al. (1990 Sep 21). A third essential DNA polymerase in S. cerevisiae.

Araki H, et al. (1992 Feb). DNA polymerase II, the probable homolog of mammalian DNA polymerase epsilon, replicates chromosomal DNA in the yeast Saccharomyces cerevisiae.

Ohya T, et al. (2000 Oct 15). Structure and function of the fourth subunit (Dpb4p) of DNA polymerase epsilon in Saccharomyces cerevisiae.

Shimizu K, et al. (2002 Oct 4). Fidelity of DNA polymerase epsilon holoenzyme from budding yeast Saccharomyces cerevisiae.

Chilkova O, et al. (2003 Apr 18). The quaternary structure of DNA polymerase epsilon from Saccharomyces cerevisiae.

Netz DJ, et al. (2011 Nov 27). Eukaryotic DNA polymerases require an iron-sulfur cluster for the formation of active complexes.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 22 genes with posterior transmembrane prediction > 50%