FOG00216
EOG8CC2G6

sce:POL3

Genes: 33

Protein description
DNA polymerase, delta


SGD Description
Catalytic subunit of DNA polymerase delta; required for chromosomal DNA replication during mitosis and meiosis, intragenic recombination, repair of double strand DNA breaks, and DNA replication during nucleotide excision repair (NER)


PomBase Description
DNA polymerase delta catalytic subunit Cdc6


AspGD Description
DNA-directed DNA polymerase


References

Boulet A, et al. (1989 Jun). Structure and function of the Saccharomyces cerevisiae CDC2 gene encoding the large subunit of DNA polymerase III.

Simon M, et al. (1991 Aug). The 3' to 5' exonuclease activity located in the DNA polymerase delta subunit of Saccharomyces cerevisiae is required for accurate replication.

Morrison A, et al. (1992 Jan 25). Nucleotide sequence of the POL3 gene encoding DNA polymerase III (delta) of Saccharomyces cerevisiae.

Johansson E, et al. (2001 Nov 23). Structure of DNA polymerase delta from Saccharomyces cerevisiae.

Wendland J, et al. (2011 Dec). Genome evolution in the eremothecium clade of the Saccharomyces complex revealed by comparative genomics.

Netz DJ, et al. (2011 Nov 27). Eukaryotic DNA polymerases require an iron-sulfur cluster for the formation of active complexes.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG00217
EOG8CC2G6

sce:CWC15

Genes: 9

Protein description
Non-essential protein involved in pre-mRNA splicing


Parent
paralog:FOG00216


SGD Description
Non-essential protein involved in pre-mRNA splicing; component of a complex containing Cef1p; has similarity to S. pombe Cwf15p


References

Ohi MD, et al. (2002 Apr). Proteomics analysis reveals stable multiprotein complexes in both fission and budding yeasts containing Myb-related Cdc5p/Cef1p, novel pre-mRNA splicing factors, and snRNAs.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%