FOG00213
EOG8KWH8S

sce:PRI2

Genes: 33

Protein description
DNA polymerase, DNA primase


SGD Description
Subunit of DNA primase; DNA primase is required for DNA synthesis and double-strand break repair


PomBase Description
DNA primase large subunit Spp2


AspGD Description
Putative DNA primase, large subunit


References

Plevani P, et al. (1988 Dec 20). The yeast DNA polymerase-primase complex: genes and proteins.

Foiani M, et al. (1989 Jul). A single essential gene, PRI2, encodes the large subunit of DNA primase in Saccharomyces cerevisiae.

Francesconi S, et al. (1991 May 1). Mutations in conserved yeast DNA primase domains impair DNA replication in vivo.

Ricke RM, et al. (2006 Jul 7). A conserved Hsp10-like domain in Mcm10 is required to stabilize the catalytic subunit of DNA polymerase-alpha in budding yeast.

Klinge S, et al. (2007 Sep). An iron-sulfur domain of the eukaryotic primase is essential for RNA primer synthesis.

Sauguet L, et al. (2010 Apr 9). Shared active site architecture between the large subunit of eukaryotic primase and DNA photolyase.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%