FOG00214
EOG879CNX

sce:POL1

Genes: 32

Protein description
DNA polymerase I


SGD Description
Catalytic subunit of the DNA polymerase I alpha-primase complex; required for the initiation of DNA replication during mitotic DNA synthesis and premeiotic DNA synthesis


PomBase Description
DNA polymerase alpha catalytic subunit


AspGD Description
DNA-directed DNA polymerase


References

Plevani P, et al. (1988 Dec 20). The yeast DNA polymerase-primase complex: genes and proteins.

Pizzagalli A, et al. (1988 Jun). DNA polymerase I gene of Saccharomyces cerevisiae: nucleotide sequence, mapping of a temperature-sensitive mutation, and protein homology with other DNA polymerases.

Mountain HA, et al. (1993 Jan). The general amino acid control regulates MET4, which encodes a methionine-pathway-specific transcriptional activator of Saccharomyces cerevisiae.

Ferrari M, et al. (1996 Apr 12). Phosphorylation of the DNA polymerase alpha-primase B subunit is dependent on its association with the p180 polypeptide.

Wittmeyer J, et al. (1997 Jul). The Saccharomyces cerevisiae DNA polymerase alpha catalytic subunit interacts with Cdc68/Spt16 and with Pob3, a protein similar to an HMG1-like protein.

Qi H, et al. (2000 Jul 15). The Saccharomyces telomere-binding protein Cdc13p interacts with both the catalytic subunit of DNA polymerase alpha and the telomerase-associated est1 protein.

Ricke RM, et al. (2006 Jul 7). A conserved Hsp10-like domain in Mcm10 is required to stabilize the catalytic subunit of DNA polymerase-alpha in budding yeast.

Chi A, et al. (2007 Feb 13). Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry.

Malavazi I, et al. (2007 Oct). Transcriptome analysis of the Aspergillus nidulans AtmA (ATM, Ataxia-Telangiectasia mutated) null mutant.

Wendland J, et al. (2011 Dec). Genome evolution in the eremothecium clade of the Saccharomyces complex revealed by comparative genomics.

Netz DJ, et al. (2011 Nov 27). Eukaryotic DNA polymerases require an iron-sulfur cluster for the formation of active complexes.

Van Damme P, et al. (2012 Jul 31). N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%