FOG00212
EOG80K6FN

sce:PRI1

Genes: 34

Protein description
DNA polymerase, DNA primase


SGD Description
Subunit of DNA primase; DNA primase is required for DNA synthesis and double-strand break repair


PomBase Description
DNA primase catalytic subunit Spp1


AspGD Description
Has domain(s) with predicted DNA primase activity and role in DNA replication, synthesis of RNA primer


References

Guiard B, et al. (1976). Complete amino acid sequence of the heme-binding core in bakers' yeast cytochrome b2 (L-(+)-lactate dehydrogenase).

Plevani P, et al. (1987 Oct 12). The nucleotide sequence of the PRI1 gene related to DNA primase in Saccharomyces cerevisiae.

Plevani P, et al. (1988 Dec 20). The yeast DNA polymerase-primase complex: genes and proteins.

Francesconi S, et al. (1991 May 1). Mutations in conserved yeast DNA primase domains impair DNA replication in vivo.

Tan S, et al. (2000 Nov). Analysis of fission yeast primase defines the checkpoint responses to aberrant S phase initiation.

Griffiths DJ, et al. (2001 Jan). Role of fission yeast primase catalytic subunit in the replication checkpoint.

Uchiyama M, et al. (2001 Jul 13). Essential role of Sna41/Cdc45 in loading of DNA polymerase alpha onto minichromosome maintenance proteins in fission yeast.

Kanoh J, et al. (2003 Feb 28). The fission yeast spSet1p is a histone H3-K4 methyltransferase that functions in telomere maintenance and DNA repair in an ATM kinase Rad3-dependent pathway.

Dahlén M, et al. (2003 May). Replication proteins influence the maintenance of telomere length and telomerase protein stability.

Yuasa T, et al. (2004 Nov). An interactive gene network for securin-separase, condensin, cohesin, Dis1/Mtc1 and histones constructed by mass transformation.

Uchiyama M, et al. (2004 Sep). The B-subunit of DNA polymerase alpha-primase associates with the origin recognition complex for initiation of DNA replication.

Yang X, et al. (2005 Jun 7). Nuclear distribution and chromatin association of DNA polymerase alpha-primase is affected by TEV protease cleavage of Cdc23 (Mcm10) in fission yeast.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%