FOG19506
EOG808KSR

sce:ENT1;ENT2

Genes: 39

SGD Description
Epsin-like protein involved in endocytosis and actin patch assembly; functionally redundant with Ent2p; binds clathrin via a clathrin-binding domain motif at C-terminus; relocalizes from bud neck to cytoplasm upon DNA replication stress; ENT1 has a paralog, ENT2, that arose from the whole genome duplication|Epsin-like protein required for endocytosis and actin patch assembly; functionally redundant with Ent1p; contains clathrin-binding motif at C-terminus; ENT2 has a paralog, ENT1, that arose from the whole genome duplication


PomBase Description
epsin


AspGD Description
Ortholog(s) have clathrin binding, ubiquitin binding activity and role in actin cortical patch assembly, actin filament organization, cellular response to drug, endocytosis


References

Wendland B, et al. (1999 Aug 16). Yeast epsins contain an essential N-terminal ENTH domain, bind clathrin and are required for endocytosis.

Watson HA, et al. (2001 Nov). In vivo role for actin-regulating kinases in endocytosis and yeast epsin phosphorylation.

Aguilar RC, et al. (2003 Mar 21). The yeast Epsin Ent1 is recruited to membranes through multiple independent interactions.

Chi A, et al. (2007 Feb 13). Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry.

Starita LM, et al. (2012 Jan). Sites of ubiquitin attachment in Saccharomyces cerevisiae.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%