FOG18974
EOG81RND0

sce:EMP24

Genes: 32

SGD Description
Component of the p24 complex; role in misfolded protein quality control; binds to GPI anchor proteins and mediates their efficient transport from the ER to the Golgi; integral membrane protein that associates with endoplasmic reticulum-derived COPII-coated vesicles


PomBase Description
COPII-coated vesicle component Emp24 (predicted)


AspGD Description
COPII vesicle membrane component; expression enhanced by maltose


References

Singer-Krüger B, et al. (1993 Jul 5). Partial purification and characterization of early and late endosomes from yeast. Identification of four novel proteins.

Schimmöller F, et al. (1995 Apr 3). The absence of Emp24p, a component of ER-derived COPII-coated vesicles, causes a defect in transport of selected proteins to the Golgi.

Belden WJ, et al. (1996 Oct 25). Erv25p, a component of COPII-coated vesicles, forms a complex with Emp24p that is required for efficient endoplasmic reticulum to Golgi transport.

Marzioch M, et al. (1999 Jun). Erp1p and Erp2p, partners for Emp24p and Erv25p in a yeast p24 complex.

Cho JH, et al. (2000 Mar 10). Proteins in the early golgi compartment of Saccharomyces cerevisiae immunoisolated by Sed5p.

Belden WJ, et al. (2001 Nov 16). Distinct roles for the cytoplasmic tail sequences of Emp24p and Erv25p in transport between the endoplasmic reticulum and Golgi complex.

Kim H, et al. (2006 Jul 25). A global topology map of the Saccharomyces cerevisiae membrane proteome.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 32 genes with posterior transmembrane prediction > 50%