FOG17940
EOG84B8J3

sce:PRP3

Genes: 33

SGD Description
Splicing factor; component of the U4/U6-U5 snRNP complex


PomBase Description
U4/U6 x U5 tri-snRNP complex subunit Prp3


AspGD Description
Ortholog(s) have role in mRNA cis splicing, via spliceosome and U4/U6 x U5 tri-snRNP complex, mitotic spindle pole body localization


References

Potashkin J, et al. (1989 Feb). Pre-mRNA splicing mutants of Schizosaccharomyces pombe.

Potashkin J, et al. (1989 Oct 11). Splicing of the U6 RNA precursor is impaired in fission yeast pre-mRNA splicing mutants.

Urushiyama S, et al. (1996 Nov 27). Isolation of novel pre-mRNA splicing mutants of Schizosaccharomyces pombe.

Anthony JG, et al. (1997 Oct). The yeast Prp3 protein is a U4/U6 snRNP protein necessary for integrity of the U4/U6 snRNP and the U4/U6.U5 tri-snRNP.

Potashkin J, et al. (1998 Sep). Cell-division-cycle defects associated with fission yeast pre-mRNA splicing mutants.

Gottschalk A, et al. (1999 Aug 16). Identification by mass spectrometry and functional analysis of novel proteins of the yeast [U4/U6.U5] tri-snRNP.

Carnahan RH, et al. (2005 Mar). Dim1p is required for efficient splicing and export of mRNA encoding lid1p, a component of the fission yeast anaphase-promoting complex.

Häcker I, et al. (2008 Nov). Localization of Prp8, Brr2, Snu114 and U4/U6 proteins in the yeast tri-snRNP by electron microscopy.

Chinen M, et al. (2010 Feb 19). Involvement of the spliceosomal U4 small nuclear RNA in heterochromatic gene silencing at fission yeast centromeres.

Wendland J, et al. (2011 Dec). Genome evolution in the eremothecium clade of the Saccharomyces complex revealed by comparative genomics.

Ren L, et al. (2011 Feb 28). Systematic two-hybrid and comparative proteomic analyses reveal novel yeast pre-mRNA splicing factors connected to Prp19.

Watanabe N, et al. (2012 Feb 3). Characterization of the ptr5+ gene involved in nuclear mRNA export in fission yeast.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Collier SE, et al. (2014 Oct 21). Structural and functional insights into the N-terminus of Schizosaccharomyces pombe Cdc5.

Swaffer MP, et al. (2016 Dec 15). CDK Substrate Phosphorylation and Ordering the Cell Cycle.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%