FOG17463
EOG85MKMM

sce:PHR1

Genes: 15

SGD Description
DNA photolyase involved in photoreactivation; repairs pyrimidine dimers in the presence of visible light; induced by DNA damage; regulated by transcriptional repressor Rph1p


AspGD Description
Ortholog(s) have deoxyribodipyrimidine photo-lyase activity, mRNA binding activity


References

Yasui A, et al. (1985). Homology between the photoreactivation genes of Saccharomyces cerevisiae and Escherichia coli.

Sancar GB, et al. (1985 Nov 25). Sequence of the Saccharomyces cerevisiae PHR1 gene and homology of the PHR1 photolyase to E. coli photolyase.

Sancar GB, et al. (1987 Nov 15). Purification of the yeast PHR1 photolyase from an Escherichia coli overproducing strain and characterization of the intrinsic chromophores of the enzyme.

Baer ME, et al. (1993 Aug 5). The role of conserved amino acids in substrate binding and discrimination by photolyase.

Goldman GH, et al. (2004 Apr). Aspergillus nidulans as a model system to characterize the DNA damage response in eukaryotes.

Weber S, et al. (2005 Feb 25). Light-driven enzymatic catalysis of DNA repair: a review of recent biophysical studies on photolyase.

Bayram O, et al. (2008 Aug). More than a repair enzyme: Aspergillus nidulans photolyase-like CryA is a regulator of sexual development.

Fischer R, et al. (2008 Jun 13). Developmental biology. Sex and poison in the dark.

Braus GH, et al. (2010 Dec). Fungal development and the COP9 signalosome.

Bayram O, et al. (2010 Nov). Spotlight on Aspergillus nidulans photosensory systems.

Bayram O, et al. (2012 Jan). Coordination of secondary metabolism and development in fungi: the velvet family of regulatory proteins.

Dyer PS, et al. (2012 Jan). Sexual development and cryptic sexuality in fungi: insights from Aspergillus species.

Krijgsheld P, et al. (2013 Mar 15). Development in Aspergillus.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%