FOG17453
EOG85MKP6

sce:TAM41

Genes: 34

SGD Description
Mitochondrial phosphatidate cytidylyltransferase (CDP-DAG synthase); required for cardiolipin biosynthesis; viability of null mutant is strain-dependent; mRNA is targeted to the bud; mutant displays defect in mitochondrial protein import, likely due to altered membrane lipid composition


PomBase Description
mitochondrial phosphatidate cytidylyltransferase Tam41 (predicted)


AspGD Description
Ortholog(s) have hyphal cell wall localization|Ortholog(s) have phosphatidate cytidylyltransferase activity, role in cardiolipin biosynthetic process and extrinsic component of mitochondrial inner membrane, mitochondrial matrix localization


References

Deutschbauer AM, et al. (2005 Dec). Quantitative trait loci mapped to single-nucleotide resolution in yeast.

Tamura Y, et al. (2006 Aug 28). Identification of Tam41 maintaining integrity of the TIM23 protein translocator complex in mitochondria.

Gallas MR, et al. (2006 Sep). Characterization of Mmp37p, a Saccharomyces cerevisiae mitochondrial matrix protein with a role in mitochondrial protein import.

Kutik S, et al. (2008 Dec 29). The translocator maintenance protein Tam41 is required for mitochondrial cardiolipin biosynthesis.

Osman C, et al. (2010 Jun 16). A mitochondrial phosphatase required for cardiolipin biosynthesis: the PGP phosphatase Gep4.

Tamura Y, et al. (2013 May 7). Tam41 is a CDP-diacylglycerol synthase required for cardiolipin biosynthesis in mitochondria.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%