FOG16866
EOG876HF1

sce:DOP1

Genes: 35

SGD Description
Golgi-localized, leucine-zipper domain containing protein; involved in endosome to Golgi transport, organization of the ER, establishing cell polarity, and morphogenesis; detected in highly purified mitochondria in high-throughput studies


PomBase Description
Dopey family protein (predicted)


AspGD Description
Ortholog(s) have role in Golgi to endosome transport, cell morphogenesis, cleistothecium development, conidium formation and endoplasmic reticulum organization, more


References

Desai JD, et al. (1977). Growth, glucose metabolism and melanin formation in biotin-deficient Aspergillus nidulans.

Pascon RC, et al. (2000 Jun). Morphogenesis in Aspergillus nidulans requires Dopey (DopA), a member of a novel family of leucine zipper-like proteins conserved from yeast to humans.

Rachidi M, et al. (2005). C21orf5, a new member of Dopey family involved in morphogenesis, could participate in neurological alterations and mental retardation in Down syndrome.

Efe JA, et al. (2005 Oct 15). Yeast Mon2p is a highly conserved protein that functions in the cytoplasm-to-vacuole transport pathway and is required for Golgi homeostasis.

Gillingham AK, et al. (2006 Jan 27). Mon2, a relative of large Arf exchange factors, recruits Dop1 to the Golgi apparatus.

Harris SD, et al. (2009 Mar). Morphology and development in Aspergillus nidulans: a complex puzzle.

Dyer PS, et al. (2012 Jan). Sexual development and cryptic sexuality in fungi: insights from Aspergillus species.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 21 genes with posterior transmembrane prediction > 50%