FOG16687
EOG87PVQP

sce:NOP1

Genes: 33

SGD Description
Histone glutamine methyltransferase, modifies H2A at Q105 in nucleolus; component of the small subunit processome complex, which is required for processing of pre-18S rRNA; ortholog of mammalian fibrillarin


PomBase Description
fibrillarin, rRNA methyltransferase


AspGD Description
Ortholog(s) have histone-glutamine methyltransferase activity, mRNA binding, rRNA methyltransferase activity and role in box C/D snoRNA 3'-end processing, histone glutamine methylation, rRNA methylation


References

Schimmang T, et al. (1989 Dec 20). A yeast nucleolar protein related to mammalian fibrillarin is associated with small nucleolar RNA and is essential for viability.

Henríquez R, et al. (1990 Feb 5). Isolation and sequencing of NOP1. A yeast gene encoding a nucleolar protein homologous to a human autoimmune antigen.

Tollervey D, et al. (1991 Mar). The small nucleolar RNP protein NOP1 (fibrillarin) is required for pre-rRNA processing in yeast.

Jansen R, et al. (1993 Jun). A U3 snoRNP protein with homology to splicing factor PRP4 and G beta domains is required for ribosomal RNA processing.

Gautier T, et al. (1997 Dec). Nucleolar KKE/D repeat proteins Nop56p and Nop58p interact with Nop1p and are required for ribosome biogenesis.

Dragon F, et al. (2002 Jun 27). A large nucleolar U3 ribonucleoprotein required for 18S ribosomal RNA biogenesis.

Xu C, et al. (2003 Jun). In vivo analysis of nucleolar proteins modified by the yeast arginine methyltransferase Hmt1/Rmt1p.

Bhabhra R, et al. (2006 Jan). Nucleolar localization of Aspergillus fumigatus CgrA is temperature-dependent.

Ukil L, et al. (2009 Apr). Nucleolar separation from chromosomes during Aspergillus nidulans mitosis can occur without spindle forces.

Wendland J, et al. (2011 Dec). Genome evolution in the eremothecium clade of the Saccharomyces complex revealed by comparative genomics.

Markina-Iñarrairaegui A, et al. (2011 Oct). Nuclear transporters in a multinucleated organism: functional and localization analyses in Aspergillus nidulans.

Starita LM, et al. (2012 Jan). Sites of ubiquitin attachment in Saccharomyces cerevisiae.

Low JK, et al. (2013 Sep 6). Analysis of the proteome of Saccharomyces cerevisiae for methylarginine.

Tessarz P, et al. (2014 Jan 23). Glutamine methylation in histone H2A is an RNA-polymerase-I-dedicated modification.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%