FOG16685
EOG87PVQV

sce:TRM9

Genes: 32

SGD Description
tRNA methyltransferase; catalyzes modification of wobble bases in tRNA anticodons to 2, 5-methoxycarbonylmethyluridine and 5-methoxycarbonylmethyl-2-thiouridine; may act as part of a complex with Trm112p; deletion mutation increases translational infidelity, including amino acid misincorporation and -1 frameshifting, and also confers resistance to zymocin; null mutant displays activation of stress responses


PomBase Description
tRNA (uridine) methyltransferase Trm9 (predicted)


AspGD Description
Ortholog(s) have tRNA (uracil) methyltransferase activity, role in cellular response to drug, chronological cell aging, tRNA methylation, tRNA wobble uridine modification and cytosol, nucleus localization


References

Kalhor HR, et al. (2003 Dec). Novel methyltransferase for modified uridine residues at the wobble position of tRNA.

Purushothaman SK, et al. (2005 Jun). Trm11p and Trm112p are both required for the formation of 2-methylguanosine at position 10 in yeast tRNA.

Létoquart J, et al. (2015 Dec 15). Insights into molecular plasticity in protein complexes from Trm9-Trm112 tRNA modifying enzyme crystal structure.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%