FOG15997
EOG89GJ2D

sce:PFY1

Genes: 32

SGD Description
Profilin; binds actin, phosphatidylinositol 4,5-bisphosphate, and polyproline regions; involved in cytoskeleton organization; required for normal timing of actin polymerization in response to thermal stress; protein abundance increases in response to DNA replication stress; highly conserved protein; human PFN1 (profilin 1) complements temperature sensitive pfy1 mutants, PFN1 mutations are a rare cause of ALS


PomBase Description
profilin


AspGD Description
Profilin


References

Oechsner U, et al. (1987 Nov 11). The cDNA and deduced amino acid sequence of profilin from Saccharomyces cerevisiae.

Magdolen V, et al. (1988 Dec). The intron-containing gene for yeast profilin (PFY) encodes a vital function.

Eads JC, et al. (1998 Aug 11). Structure determination and characterization of Saccharomyces cerevisiae profilin.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%