FOG15834
EOG89ZW4G

sce:EPL1

Genes: 33

SGD Description
Subunit of NuA4, an essential histone H4/H2A acetyltransferase complex; conserved region at N-terminus is essential for interaction with the NPC (nucleosome core particle); required for autophagy; homologous to Drosophila Enhancer of Polycomb; coding sequence contains length polymorphisms in different strains


PomBase Description
NuA4 histone acetyltransferase complex Epl1


AspGD Description
Ortholog(s) have role in histone acetylation and NuA4 histone acetyltransferase complex localization


References

Stankunas K, et al. (1998 Oct). The enhancer of polycomb gene of Drosophila encodes a chromatin protein conserved in yeast and mammals.

Galarneau L, et al. (2000 Jun). Multiple links between the NuA4 histone acetyltransferase complex and epigenetic control of transcription.

Boudreault AA, et al. (2003 Jun 1). Yeast enhancer of polycomb defines global Esa1-dependent acetylation of chromatin.

Oki M, et al. (2004 Mar). Barrier proteins remodel and modify chromatin to restrict silenced domains.

Kobor MS, et al. (2004 May). A protein complex containing the conserved Swi2/Snf2-related ATPase Swr1p deposits histone variant H2A.Z into euchromatin.

Zhang H, et al. (2004 Nov). The Yaf9 component of the SWR1 and NuA4 complexes is required for proper gene expression, histone H4 acetylation, and Htz1 replacement near telomeres.

Krogan NJ, et al. (2004 Sep 14). Regulation of chromosome stability by the histone H2A variant Htz1, the Swr1 chromatin remodeling complex, and the histone acetyltransferase NuA4.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%