FOG15833
EOG89ZW4J

sce:GEM1

Genes: 33

SGD Description
Outer mitochondrial membrane GTPase, subunit of the ERMES complex; potential regulatory subunit of the ERMES complex that links the ER to mitochondria and may promote inter-organellar calcium and phospholipid exchange as well as coordinating mitochondrial DNA replication and growth; cells lacking Gem1p contain collapsed, globular, or grape-like mitochondria; ortholog of metazoan Miro GTPases


PomBase Description
ERMES complex GTPase subunit Gem1 (predicted)


AspGD Description
Ortholog(s) have GTPase activity, calcium ion binding activity and role in mitochondrion inheritance, mitochondrion-ER tethering, phospholipid homeostasis, regulation of mitochondrion organization


References

Wolff AM, et al. (1999 Mar 30). The open reading frame YAL048c affects the secretion of proteinase A in S. cerevisiae.

Frederick RL, et al. (2004 Oct 11). Yeast Miro GTPase, Gem1p, regulates mitochondrial morphology via a novel pathway.

Zahedi RP, et al. (2006 Mar). Proteomic analysis of the yeast mitochondrial outer membrane reveals accumulation of a subclass of preproteins.

Wendland J, et al. (2011 Dec). Genome evolution in the eremothecium clade of the Saccharomyces complex revealed by comparative genomics.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 33 genes with posterior transmembrane prediction > 50%