FOG15474
EOG8BVQB9

sce:TRM82

Genes: 32

SGD Description
Catalytic subunit of a tRNA methyltransferase complex; Trm8p and Trm82p comprise an enzyme that catalyzes a methyl-transfer from S-adenosyl-l-methionine to the N(7) atom of guanine at position 46 in tRNA; Trm8 lacks catalytic activity if not bound to Trm82p; relocalizes to the cytosol in response to hypoxia


PomBase Description
tRNA (guanine-N7-)-methyltransferase subunit Trm82 (predicted)


AspGD Description
Ortholog(s) have cytosol, nucleus localization


References

Alexandrov A, et al. (2002 Oct). Two proteins that form a complex are required for 7-methylguanosine modification of yeast tRNA.

Chibana H, et al. (2005 Aug). Sequence finishing and gene mapping for Candida albicans chromosome 7 and syntenic analysis against the Saccharomyces cerevisiae genome.

Alexandrov A, et al. (2005 May). tRNA m7G methyltransferase Trm8p/Trm82p: evidence linking activity to a growth phenotype and implicating Trm82p in maintaining levels of active Trm8p.

Alexandrov A, et al. (2006 Jan 6). Rapid tRNA decay can result from lack of nonessential modifications.

Matsumoto K, et al. (2007 Apr 17). RNA recognition mechanism of eukaryote tRNA (m7G46) methyltransferase (Trm8-Trm82 complex).

Leulliot N, et al. (2008 Jan). Structure of the yeast tRNA m7G methylation complex.

Van Damme P, et al. (2012 Jul 31). N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%