FOG15007
EOG8D254S

sce:SPC110

Genes: 5

SGD Description
Inner plaque spindle pole body (SPB) component; ortholog of human kendrin; involved in connecting nuclear microtubules to SPB; interacts with Tub4p-complex and calmodulin; phosphorylated by Mps1p in cell cycle-dependent manner


References

Mirzayan C, et al. (1992 Mar). The NUF1 gene encodes an essential coiled-coil related protein that is a potential component of the yeast nucleoskeleton.

Geiser JR, et al. (1993 Dec). The essential mitotic target of calmodulin is the 110-kilodalton component of the spindle pole body in Saccharomyces cerevisiae.

Kilmartin JV, et al. (1993 Dec). A spacer protein in the Saccharomyces cerevisiae spindle poly body whose transcript is cell cycle-regulated.

Knop M, et al. (1997 Dec 1). Spc98p and Spc97p of the yeast gamma-tubulin complex mediate binding to the spindle pole body via their interaction with Spc110p.

Elliott S, et al. (1999 May 25). Spc29p is a component of the Spc110p subcomplex and is essential for spindle pole body duplication.

Friedman DB, et al. (2001 May 25). Yeast Mps1p phosphorylates the spindle pole component Spc110p in the N-terminal domain.

Muller EG, et al. (2005 Jul). The organization of the core proteins of the yeast spindle pole body.

Huisman SM, et al. (2007 Feb 1). Phosphorylation of Spc110p by Cdc28p-Clb5p kinase contributes to correct spindle morphogenesis in S. cerevisiae.

Wendland J, et al. (2011 Dec). Genome evolution in the eremothecium clade of the Saccharomyces complex revealed by comparative genomics.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 2 genes with posterior transmembrane prediction > 50%